Accelerated development of instability-induced osteoarthritis in transgenic mice overexpressing SOST

Sclerostin (SOST), acting as a Wnt antagonist, has been shown to play a key role in regulating bone homestasis, and has also been linked to osteoarthritis (OA) development. Here, we investigated whether overexpressing SOST could affect OA development after destabilization of the medial meniscus (DMM...

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Veröffentlicht in:	International journal of clinical and experimental pathology 2017-01, Vol.10 (11), p.10830-10840
Hauptverfasser:	Zhou, Sheng, Ge, Yuxiang, Li, Yixuan, Bao, Zhengyuan, Yao, Chen, Teng, Huajian, Jiang, Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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