Osteoprotective action of low-salt diet requires myeloid cell-derived NFAT5

Dietary salt consumption leads to cutaneous Na+ storage and is associated with various disorders, including osteopenia. Here, we explore the impact of Na+ and the osmoprotective transcription factor nuclear factor of activated T cell 5 (NFAT5) on bone density and osteoclastogenesis. Compared with tr...

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Veröffentlicht in:JCI insight 2019-12, Vol.4 (23)
Hauptverfasser: Schröder, Agnes, Neubert, Patrick, Titze, Jens, Bozec, Aline, Neuhofer, Wolfgang, Proff, Peter, Kirschneck, Christian, Jantsch, Jonathan
Format: Artikel
Sprache:eng
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