Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks

Intraoperative diagnosis is essential for providing safe and effective care during cancer surgery 1 . The existing workflow for intraoperative diagnosis based on hematoxylin and eosin staining of processed tissue is time, resource and labor intensive 2 , 3 . Moreover, interpretation of intraoperativ...

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Veröffentlicht in:	Nature medicine 2020-01, Vol.26 (1), p.52-58
Hauptverfasser:	Hollon, Todd C., Pandian, Balaji, Adapa, Arjun R., Urias, Esteban, Save, Akshay V., Khalsa, Siri Sahib S., Eichberg, Daniel G., D’Amico, Randy S., Farooq, Zia U., Lewis, Spencer, Petridis, Petros D., Marie, Tamara, Shah, Ashish H., Garton, Hugh J. L., Maher, Cormac O., Heth, Jason A., McKean, Erin L., Sullivan, Stephen E., Hervey-Jumper, Shawn L., Patil, Parag G., Thompson, B. Gregory, Sagher, Oren, McKhann, Guy M., Komotar, Ricardo J., Ivan, Michael E., Snuderl, Matija, Otten, Marc L., Johnson, Timothy D., Sisti, Michael B., Bruce, Jeffrey N., Muraszko, Karin M., Trautman, Jay, Freudiger, Christian W., Canoll, Peter, Lee, Honglak, Camelo-Piragua, Sandra, Orringer, Daniel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/114/1305 631/1647/527/1821 631/67/2321 692/308/575 Algorithms Artificial intelligence Artificial neural networks Biomedical and Life Sciences Biomedicine Brain Brain cancer Brain Neoplasms - diagnosis Brain Neoplasms - diagnostic imaging Brain tumors Cancer Cancer Research Clinical trials Clinical Trials as Topic Computer Systems Deep Learning Diagnosis Diagnostic systems Feature recognition Health aspects Histology Humans Image Processing, Computer-Assisted Image segmentation Infectious Diseases Letter Medical imaging Metabolic Diseases Molecular Medicine Monitoring, Intraoperative Neural networks Neural Networks, Computer Neuroimaging Neurosciences Pathology Probability Raman spectroscopy Real time Spectrum Analysis, Raman Tumors Workflow
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