C3435T polymorphism in the MDR1 gene and breast cancer risk in northeastern Mexico

The multidrug resistance gene 1 ( ) encodes a membrane-bound phosphoglycoprotein (P-gp). It functions as a transmembrane efflux pump for various structurally unrelated carcinogens and toxins. Polymorphism C3435T of has been investigated for its association with breast cancer in different populations...

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Veröffentlicht in:International journal of clinical and experimental pathology 2018-01, Vol.11 (2), p.904-909
Hauptverfasser: Jaramillo-Rangel, Gilberto, Ortega-Martínez, Marta, Cerda-Flores, Ricardo M, Barrera-Saldaña, Hugo A
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Sprache:eng
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