Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis
The aim of this systematic review was to examine the effect of 2% chlorhexidine following acid etching on the microtensile bond strength of resin restorations for different follow-up times. A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in...
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| Veröffentlicht in: | Medicina (Kaunas, Lithuania) Lithuania), 2019-12, Vol.55 (12), p.769 |
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| creator | Hamdan-Nassar, Tasnim Bellot-Arcís, Carlos Paredes-Gallardo, Vanessa García-Sanz, Verónica Pascual-Moscardó, Agustín Almerich-Silla, José Manuel Montiel-Company, José María |
| description | The aim of this systematic review was to examine the effect of 2% chlorhexidine following acid etching on the microtensile bond strength of resin restorations for different follow-up times.
A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in vivo studies published up to December 2018 with an experimental group treated with a 2% chlorhexidine solution following acid etching and a control group were included, wherein the final restoration used a resin composite in both the groups.
Twenty-one articles were identified for qualitative analysis and 18 for meta-analysis. The difference in the means of microtensile bond strength between the two groups was calculated for the different follow-up times. The differences were significant for 6 months (4.30 MPa; 95% CI 2.72-5.89), 12 months (8.41 MPa; 95% CI 4.93-11.88), and 2-5 years including aged and thermocycling samples (9.08 MPa; 95% CI 5.36-12.81). There were no significant differences for the type of adhesive used. A meta-regression model showed a significant effect of time on the microtensile bond strength.
The application of a 2% chlorhexidine solution after acid etching increased the microtensile bond strength significantly for follow-up times of 6 months or more. The adhesive type had no influence. |
| doi_str_mv | 10.3390/medicina55120769 |
| format | Article |
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A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in vivo studies published up to December 2018 with an experimental group treated with a 2% chlorhexidine solution following acid etching and a control group were included, wherein the final restoration used a resin composite in both the groups.
Twenty-one articles were identified for qualitative analysis and 18 for meta-analysis. The difference in the means of microtensile bond strength between the two groups was calculated for the different follow-up times. The differences were significant for 6 months (4.30 MPa; 95% CI 2.72-5.89), 12 months (8.41 MPa; 95% CI 4.93-11.88), and 2-5 years including aged and thermocycling samples (9.08 MPa; 95% CI 5.36-12.81). There were no significant differences for the type of adhesive used. A meta-regression model showed a significant effect of time on the microtensile bond strength.
The application of a 2% chlorhexidine solution after acid etching increased the microtensile bond strength significantly for follow-up times of 6 months or more. The adhesive type had no influence.</description><identifier>ISSN: 1648-9144</identifier><identifier>ISSN: 1010-660X</identifier><identifier>EISSN: 1648-9144</identifier><identifier>DOI: 10.3390/medicina55120769</identifier><identifier>PMID: 31810222</identifier><language>eng</language><publisher>Switzerland: MDPI</publisher><subject>Acid Etching, Dental ; Chlorhexidine - pharmacology ; Composite Resins ; Dental Cements - pharmacology ; Humans ; Review ; Tensile Strength - drug effects</subject><ispartof>Medicina (Kaunas, Lithuania), 2019-12, Vol.55 (12), p.769</ispartof><rights>2019 by the authors. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-a045c8f5f41965eefe5062a034cf6008c818a6be709f6fe9d49de1d225b50a993</citedby><cites>FETCH-LOGICAL-c396t-a045c8f5f41965eefe5062a034cf6008c818a6be709f6fe9d49de1d225b50a993</cites><orcidid>0000-0001-9605-3833 ; 0000-0002-3952-7681</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955988/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955988/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,862,883,27911,27912,53778,53780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31810222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hamdan-Nassar, Tasnim</creatorcontrib><creatorcontrib>Bellot-Arcís, Carlos</creatorcontrib><creatorcontrib>Paredes-Gallardo, Vanessa</creatorcontrib><creatorcontrib>García-Sanz, Verónica</creatorcontrib><creatorcontrib>Pascual-Moscardó, Agustín</creatorcontrib><creatorcontrib>Almerich-Silla, José Manuel</creatorcontrib><creatorcontrib>Montiel-Company, José María</creatorcontrib><title>Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis</title><title>Medicina (Kaunas, Lithuania)</title><addtitle>Medicina (Kaunas)</addtitle><description>The aim of this systematic review was to examine the effect of 2% chlorhexidine following acid etching on the microtensile bond strength of resin restorations for different follow-up times.
A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in vivo studies published up to December 2018 with an experimental group treated with a 2% chlorhexidine solution following acid etching and a control group were included, wherein the final restoration used a resin composite in both the groups.
Twenty-one articles were identified for qualitative analysis and 18 for meta-analysis. The difference in the means of microtensile bond strength between the two groups was calculated for the different follow-up times. The differences were significant for 6 months (4.30 MPa; 95% CI 2.72-5.89), 12 months (8.41 MPa; 95% CI 4.93-11.88), and 2-5 years including aged and thermocycling samples (9.08 MPa; 95% CI 5.36-12.81). There were no significant differences for the type of adhesive used. A meta-regression model showed a significant effect of time on the microtensile bond strength.
The application of a 2% chlorhexidine solution after acid etching increased the microtensile bond strength significantly for follow-up times of 6 months or more. The adhesive type had no influence.</description><subject>Acid Etching, Dental</subject><subject>Chlorhexidine - pharmacology</subject><subject>Composite Resins</subject><subject>Dental Cements - pharmacology</subject><subject>Humans</subject><subject>Review</subject><subject>Tensile Strength - drug effects</subject><issn>1648-9144</issn><issn>1010-660X</issn><issn>1648-9144</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUUtv1DAQthCoL3rvqfIFiUvAj9iJe0BaVltAalWpwNnyOuONK69dbG-h_76JWqrCZR6ame-bmQ-hE0o-cK7Ixy0M3vpohKCMdFK9QgdUtn2jaNu-fhHvo8NSbgjhTHRsD-1z2lPCGDtAdyvnwFacHGbv8HIMKY_wxw8-Aj5PIaTfPm7wwvoBr6od5yRFfOltThVi8QHw5xQH_L1miJs6zkDXUHycbU3ZVJ9iOcMLfAnVNItown3x5S1640wocPzkj9DP89WP5dfm4urLt-XiorFcydoY0grbO-FaqqQAcCCIZIbw1jpJSG972hu5ho4oJx2ooVUD0IExsRbEKMWP0KdH3NvdenqWhVizCfo2-63J9zoZr_-tRD_qTbrTUgmh-n4CeP8EkNOv3XSS3vpiIQQTIe2KZpyxTtCum7nIY-v0m1IyuGcaSvQsl_5frmnk9OV6zwN_9eEP376UQA</recordid><startdate>20191202</startdate><enddate>20191202</enddate><creator>Hamdan-Nassar, Tasnim</creator><creator>Bellot-Arcís, Carlos</creator><creator>Paredes-Gallardo, Vanessa</creator><creator>García-Sanz, Verónica</creator><creator>Pascual-Moscardó, Agustín</creator><creator>Almerich-Silla, José Manuel</creator><creator>Montiel-Company, José María</creator><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9605-3833</orcidid><orcidid>https://orcid.org/0000-0002-3952-7681</orcidid></search><sort><creationdate>20191202</creationdate><title>Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis</title><author>Hamdan-Nassar, Tasnim ; Bellot-Arcís, Carlos ; Paredes-Gallardo, Vanessa ; García-Sanz, Verónica ; Pascual-Moscardó, Agustín ; Almerich-Silla, José Manuel ; Montiel-Company, José María</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-a045c8f5f41965eefe5062a034cf6008c818a6be709f6fe9d49de1d225b50a993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acid Etching, Dental</topic><topic>Chlorhexidine - pharmacology</topic><topic>Composite Resins</topic><topic>Dental Cements - pharmacology</topic><topic>Humans</topic><topic>Review</topic><topic>Tensile Strength - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hamdan-Nassar, Tasnim</creatorcontrib><creatorcontrib>Bellot-Arcís, Carlos</creatorcontrib><creatorcontrib>Paredes-Gallardo, Vanessa</creatorcontrib><creatorcontrib>García-Sanz, Verónica</creatorcontrib><creatorcontrib>Pascual-Moscardó, Agustín</creatorcontrib><creatorcontrib>Almerich-Silla, José Manuel</creatorcontrib><creatorcontrib>Montiel-Company, José María</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicina (Kaunas, Lithuania)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hamdan-Nassar, Tasnim</au><au>Bellot-Arcís, Carlos</au><au>Paredes-Gallardo, Vanessa</au><au>García-Sanz, Verónica</au><au>Pascual-Moscardó, Agustín</au><au>Almerich-Silla, José Manuel</au><au>Montiel-Company, José María</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis</atitle><jtitle>Medicina (Kaunas, Lithuania)</jtitle><addtitle>Medicina (Kaunas)</addtitle><date>2019-12-02</date><risdate>2019</risdate><volume>55</volume><issue>12</issue><spage>769</spage><pages>769-</pages><issn>1648-9144</issn><issn>1010-660X</issn><eissn>1648-9144</eissn><abstract>The aim of this systematic review was to examine the effect of 2% chlorhexidine following acid etching on the microtensile bond strength of resin restorations for different follow-up times.
A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in vivo studies published up to December 2018 with an experimental group treated with a 2% chlorhexidine solution following acid etching and a control group were included, wherein the final restoration used a resin composite in both the groups.
Twenty-one articles were identified for qualitative analysis and 18 for meta-analysis. The difference in the means of microtensile bond strength between the two groups was calculated for the different follow-up times. The differences were significant for 6 months (4.30 MPa; 95% CI 2.72-5.89), 12 months (8.41 MPa; 95% CI 4.93-11.88), and 2-5 years including aged and thermocycling samples (9.08 MPa; 95% CI 5.36-12.81). There were no significant differences for the type of adhesive used. A meta-regression model showed a significant effect of time on the microtensile bond strength.
The application of a 2% chlorhexidine solution after acid etching increased the microtensile bond strength significantly for follow-up times of 6 months or more. The adhesive type had no influence.</abstract><cop>Switzerland</cop><pub>MDPI</pub><pmid>31810222</pmid><doi>10.3390/medicina55120769</doi><orcidid>https://orcid.org/0000-0001-9605-3833</orcidid><orcidid>https://orcid.org/0000-0002-3952-7681</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1648-9144 |
| ispartof | Medicina (Kaunas, Lithuania), 2019-12, Vol.55 (12), p.769 |
| issn | 1648-9144 1010-660X 1648-9144 |
| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Acid Etching, Dental Chlorhexidine - pharmacology Composite Resins Dental Cements - pharmacology Humans Review Tensile Strength - drug effects |
| title | Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis |
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