A randomized clinical trial of comprehensive education and care program compared to basic care for reducing anxiety and depression and improving quality of life and survival in patients with hepatocellular carcinoma who underwent surgery
This study aimed to investigate the effect of comprehensive education and care (CEC) program on anxiety, depression, quality of life, and survival in patients with hepatocellular carcinoma (HCC) who underwent surgical resection.Totally 136 patients with HCC who underwent hepatectomy were randomly as...
Gespeichert in:
| Veröffentlicht in: | Medicine (Baltimore) 2019-11, Vol.98 (44), p.e17552-e17552 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e17552 |
|---|---|
| container_issue | 44 |
| container_start_page | e17552 |
| container_title | Medicine (Baltimore) |
| container_volume | 98 |
| creator | Wang, Jingjing Yan, Chenli Fu, Adan |
| description | This study aimed to investigate the effect of comprehensive education and care (CEC) program on anxiety, depression, quality of life, and survival in patients with hepatocellular carcinoma (HCC) who underwent surgical resection.Totally 136 patients with HCC who underwent hepatectomy were randomly assigned to CEC group and control group as 1:1 ratio. CEC group received health education, psychological nursing, caring activity, and telephone condolence, whereas control group received basic health education and rehabilitation for 12 months. Anxiety and depression were assessed by Hospital Anxiety and Depression Scale (HADS); quality of life was evaluated using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30).HADS-Anxiety (HADS-A) score was decreased at 9 month (M9) and M12, and reduction in HADS-A score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of anxiety patients was less, but anxiety severity was similar in CEC group compared with control group. HADS-Depression (HADS-D) score was decreased at M12, and reduction in HADS-D score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of depression patients were less but depression severity was similar in CEC group compared with control group. In addition, QLQ-C30 global health status and functional score was increased at M12, and score improvement (M12-M0) was greater in CEC group compared with control group. In addition, overall survival was longer in CEC group compared with control group.CEC relieves anxiety and depression, improves quality of life, and prolongs survival in patients with HCC underwent surgical resection. |
| doi_str_mv | 10.1097/MD.0000000000017552 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6946196</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2312552999</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5008-f7485a6675e703222ff87693bc9f3bf7f58ff68a4d21337427d851819f6c29183</originalsourceid><addsrcrecordid>eNpdkstu1DAUhiMEoqXwBEjISzYpvsR2vEGqWm5SKzawtjzO8cTgxFM7mWF4Z94BZ6YtFy9sWef7__9YPlX1kuBzgpV8c3N1jv8sIjmnj6pTwpmouRLN4-oUY8prqWRzUj3L-VuBmKTN0-qEEdEqydvT6tcFSmbs4uB_Qods8KO3JqAp-bJHh2wcNgl6GLPfAoJutmbycURFg6xJgDYprpMZDmC5d2iKaGWyt8eyiwmlRebHdRH98DDtD-IOim_O916-xMTtAt3OJvgClfDgHRyqeU5bvy0d-RFtSgMwThnt_NSjHso9WghhDiYtmSUpDgbt-ojmsYO0K_BisIa0f149cSZkeHF3nlVf37_7cvmxvv784dPlxXVtOcZt7WTTciOE5CAxo5Q610qh2Moqx1ZOOt46J1rTdJQwJhsqu5aTlignLFWkZWfV26PvZl4N0NnSQjJBb5IfTNrraLz-tzL6Xq_jVgvVCKJEMXh9Z5Di7Qx50oPPyyvNCHHOmjJCy38rpQrKjqhNMecE7iGGYL0Mir650v8PSlG9-rvDB839ZBSgOQK7GCZI-XuYd5B0DyZM_cGPS0VriokiBBNcL9Yt-w26iNBh</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2312552999</pqid></control><display><type>article</type><title>A randomized clinical trial of comprehensive education and care program compared to basic care for reducing anxiety and depression and improving quality of life and survival in patients with hepatocellular carcinoma who underwent surgery</title><source>Wolters Kluwer Open Health</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>IngentaConnect Free/Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Wang, Jingjing ; Yan, Chenli ; Fu, Adan</creator><creatorcontrib>Wang, Jingjing ; Yan, Chenli ; Fu, Adan</creatorcontrib><description>This study aimed to investigate the effect of comprehensive education and care (CEC) program on anxiety, depression, quality of life, and survival in patients with hepatocellular carcinoma (HCC) who underwent surgical resection.Totally 136 patients with HCC who underwent hepatectomy were randomly assigned to CEC group and control group as 1:1 ratio. CEC group received health education, psychological nursing, caring activity, and telephone condolence, whereas control group received basic health education and rehabilitation for 12 months. Anxiety and depression were assessed by Hospital Anxiety and Depression Scale (HADS); quality of life was evaluated using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30).HADS-Anxiety (HADS-A) score was decreased at 9 month (M9) and M12, and reduction in HADS-A score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of anxiety patients was less, but anxiety severity was similar in CEC group compared with control group. HADS-Depression (HADS-D) score was decreased at M12, and reduction in HADS-D score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of depression patients were less but depression severity was similar in CEC group compared with control group. In addition, QLQ-C30 global health status and functional score was increased at M12, and score improvement (M12-M0) was greater in CEC group compared with control group. In addition, overall survival was longer in CEC group compared with control group.CEC relieves anxiety and depression, improves quality of life, and prolongs survival in patients with HCC underwent surgical resection.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000017552</identifier><identifier>PMID: 31689758</identifier><language>eng</language><publisher>United States: the Author(s). Published by Wolters Kluwer Health, Inc</publisher><subject>Adult ; Aged ; Anxiety - therapy ; Carcinoma, Hepatocellular - psychology ; Carcinoma, Hepatocellular - rehabilitation ; Carcinoma, Hepatocellular - surgery ; Counseling - methods ; Depression - therapy ; Female ; Health Status ; Humans ; Liver Neoplasms - psychology ; Liver Neoplasms - rehabilitation ; Liver Neoplasms - surgery ; Male ; Middle Aged ; Observational Study ; Patient Education as Topic - methods ; Psychotherapy, Group - methods ; Quality of Life ; Telephone</subject><ispartof>Medicine (Baltimore), 2019-11, Vol.98 (44), p.e17552-e17552</ispartof><rights>the Author(s). Published by Wolters Kluwer Health, Inc.</rights><rights>Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5008-f7485a6675e703222ff87693bc9f3bf7f58ff68a4d21337427d851819f6c29183</citedby><cites>FETCH-LOGICAL-c5008-f7485a6675e703222ff87693bc9f3bf7f58ff68a4d21337427d851819f6c29183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946196/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946196/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31689758$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Jingjing</creatorcontrib><creatorcontrib>Yan, Chenli</creatorcontrib><creatorcontrib>Fu, Adan</creatorcontrib><title>A randomized clinical trial of comprehensive education and care program compared to basic care for reducing anxiety and depression and improving quality of life and survival in patients with hepatocellular carcinoma who underwent surgery</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>This study aimed to investigate the effect of comprehensive education and care (CEC) program on anxiety, depression, quality of life, and survival in patients with hepatocellular carcinoma (HCC) who underwent surgical resection.Totally 136 patients with HCC who underwent hepatectomy were randomly assigned to CEC group and control group as 1:1 ratio. CEC group received health education, psychological nursing, caring activity, and telephone condolence, whereas control group received basic health education and rehabilitation for 12 months. Anxiety and depression were assessed by Hospital Anxiety and Depression Scale (HADS); quality of life was evaluated using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30).HADS-Anxiety (HADS-A) score was decreased at 9 month (M9) and M12, and reduction in HADS-A score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of anxiety patients was less, but anxiety severity was similar in CEC group compared with control group. HADS-Depression (HADS-D) score was decreased at M12, and reduction in HADS-D score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of depression patients were less but depression severity was similar in CEC group compared with control group. In addition, QLQ-C30 global health status and functional score was increased at M12, and score improvement (M12-M0) was greater in CEC group compared with control group. In addition, overall survival was longer in CEC group compared with control group.CEC relieves anxiety and depression, improves quality of life, and prolongs survival in patients with HCC underwent surgical resection.</description><subject>Adult</subject><subject>Aged</subject><subject>Anxiety - therapy</subject><subject>Carcinoma, Hepatocellular - psychology</subject><subject>Carcinoma, Hepatocellular - rehabilitation</subject><subject>Carcinoma, Hepatocellular - surgery</subject><subject>Counseling - methods</subject><subject>Depression - therapy</subject><subject>Female</subject><subject>Health Status</subject><subject>Humans</subject><subject>Liver Neoplasms - psychology</subject><subject>Liver Neoplasms - rehabilitation</subject><subject>Liver Neoplasms - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Observational Study</subject><subject>Patient Education as Topic - methods</subject><subject>Psychotherapy, Group - methods</subject><subject>Quality of Life</subject><subject>Telephone</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkstu1DAUhiMEoqXwBEjISzYpvsR2vEGqWm5SKzawtjzO8cTgxFM7mWF4Z94BZ6YtFy9sWef7__9YPlX1kuBzgpV8c3N1jv8sIjmnj6pTwpmouRLN4-oUY8prqWRzUj3L-VuBmKTN0-qEEdEqydvT6tcFSmbs4uB_Qods8KO3JqAp-bJHh2wcNgl6GLPfAoJutmbycURFg6xJgDYprpMZDmC5d2iKaGWyt8eyiwmlRebHdRH98DDtD-IOim_O916-xMTtAt3OJvgClfDgHRyqeU5bvy0d-RFtSgMwThnt_NSjHso9WghhDiYtmSUpDgbt-ojmsYO0K_BisIa0f149cSZkeHF3nlVf37_7cvmxvv784dPlxXVtOcZt7WTTciOE5CAxo5Q610qh2Moqx1ZOOt46J1rTdJQwJhsqu5aTlignLFWkZWfV26PvZl4N0NnSQjJBb5IfTNrraLz-tzL6Xq_jVgvVCKJEMXh9Z5Di7Qx50oPPyyvNCHHOmjJCy38rpQrKjqhNMecE7iGGYL0Mir650v8PSlG9-rvDB839ZBSgOQK7GCZI-XuYd5B0DyZM_cGPS0VriokiBBNcL9Yt-w26iNBh</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Wang, Jingjing</creator><creator>Yan, Chenli</creator><creator>Fu, Adan</creator><general>the Author(s). Published by Wolters Kluwer Health, Inc</general><general>Wolters Kluwer Health</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20191101</creationdate><title>A randomized clinical trial of comprehensive education and care program compared to basic care for reducing anxiety and depression and improving quality of life and survival in patients with hepatocellular carcinoma who underwent surgery</title><author>Wang, Jingjing ; Yan, Chenli ; Fu, Adan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5008-f7485a6675e703222ff87693bc9f3bf7f58ff68a4d21337427d851819f6c29183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anxiety - therapy</topic><topic>Carcinoma, Hepatocellular - psychology</topic><topic>Carcinoma, Hepatocellular - rehabilitation</topic><topic>Carcinoma, Hepatocellular - surgery</topic><topic>Counseling - methods</topic><topic>Depression - therapy</topic><topic>Female</topic><topic>Health Status</topic><topic>Humans</topic><topic>Liver Neoplasms - psychology</topic><topic>Liver Neoplasms - rehabilitation</topic><topic>Liver Neoplasms - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Observational Study</topic><topic>Patient Education as Topic - methods</topic><topic>Psychotherapy, Group - methods</topic><topic>Quality of Life</topic><topic>Telephone</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Jingjing</creatorcontrib><creatorcontrib>Yan, Chenli</creatorcontrib><creatorcontrib>Fu, Adan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Jingjing</au><au>Yan, Chenli</au><au>Fu, Adan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A randomized clinical trial of comprehensive education and care program compared to basic care for reducing anxiety and depression and improving quality of life and survival in patients with hepatocellular carcinoma who underwent surgery</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2019-11-01</date><risdate>2019</risdate><volume>98</volume><issue>44</issue><spage>e17552</spage><epage>e17552</epage><pages>e17552-e17552</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>This study aimed to investigate the effect of comprehensive education and care (CEC) program on anxiety, depression, quality of life, and survival in patients with hepatocellular carcinoma (HCC) who underwent surgical resection.Totally 136 patients with HCC who underwent hepatectomy were randomly assigned to CEC group and control group as 1:1 ratio. CEC group received health education, psychological nursing, caring activity, and telephone condolence, whereas control group received basic health education and rehabilitation for 12 months. Anxiety and depression were assessed by Hospital Anxiety and Depression Scale (HADS); quality of life was evaluated using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30).HADS-Anxiety (HADS-A) score was decreased at 9 month (M9) and M12, and reduction in HADS-A score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of anxiety patients was less, but anxiety severity was similar in CEC group compared with control group. HADS-Depression (HADS-D) score was decreased at M12, and reduction in HADS-D score (M12-M0) was greater in CEC group compared with control group. At M12, percentage of depression patients were less but depression severity was similar in CEC group compared with control group. In addition, QLQ-C30 global health status and functional score was increased at M12, and score improvement (M12-M0) was greater in CEC group compared with control group. In addition, overall survival was longer in CEC group compared with control group.CEC relieves anxiety and depression, improves quality of life, and prolongs survival in patients with HCC underwent surgical resection.</abstract><cop>United States</cop><pub>the Author(s). Published by Wolters Kluwer Health, Inc</pub><pmid>31689758</pmid><doi>10.1097/MD.0000000000017552</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0025-7974 |
| ispartof | Medicine (Baltimore), 2019-11, Vol.98 (44), p.e17552-e17552 |
| issn | 0025-7974 1536-5964 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6946196 |
| source | Wolters Kluwer Open Health; MEDLINE; DOAJ Directory of Open Access Journals; IngentaConnect Free/Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Aged Anxiety - therapy Carcinoma, Hepatocellular - psychology Carcinoma, Hepatocellular - rehabilitation Carcinoma, Hepatocellular - surgery Counseling - methods Depression - therapy Female Health Status Humans Liver Neoplasms - psychology Liver Neoplasms - rehabilitation Liver Neoplasms - surgery Male Middle Aged Observational Study Patient Education as Topic - methods Psychotherapy, Group - methods Quality of Life Telephone |
| title | A randomized clinical trial of comprehensive education and care program compared to basic care for reducing anxiety and depression and improving quality of life and survival in patients with hepatocellular carcinoma who underwent surgery |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T22%3A09%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20randomized%20clinical%20trial%20of%20comprehensive%20education%20and%20care%20program%20compared%20to%20basic%20care%20for%20reducing%20anxiety%20and%20depression%20and%20improving%20quality%20of%20life%20and%20survival%20in%20patients%20with%20hepatocellular%20carcinoma%20who%20underwent%20surgery&rft.jtitle=Medicine%20(Baltimore)&rft.au=Wang,%20Jingjing&rft.date=2019-11-01&rft.volume=98&rft.issue=44&rft.spage=e17552&rft.epage=e17552&rft.pages=e17552-e17552&rft.issn=0025-7974&rft.eissn=1536-5964&rft_id=info:doi/10.1097/MD.0000000000017552&rft_dat=%3Cproquest_pubme%3E2312552999%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2312552999&rft_id=info:pmid/31689758&rfr_iscdi=true |