The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model

Objective Macrolides have been reported to reduce the exacerbation of severe asthma. The aim of this study was to clarify the effects and mechanisms of EM900, a non-antibiotic macrolide, on allergic airway inflammation. Methods Mice were sensitized and challenged by house dust mite (HDM), then expos...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Inflammation research 2020-01, Vol.69 (1), p.139-151
Hauptverfasser:	Sadamatsu, Hironori, Takahashi, Koichiro, Tashiro, Hiroki, Kato, Go, Noguchi, Yoshihiko, Kurata, Keigo, Ōmura, Satoshi, Kimura, Shinya, Sunazuka, Toshiaki, Sueoka-Aragane, Naoko
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergology Alveoli Antibiotics Asthma Biomedical and Life Sciences Biomedicine Bronchus Cytokines Dermatology Drug resistance Flow cytometry House dust Immunology Inflammation Interleukin 13 Interleukin 5 Interleukin 6 Lungs Macrophage inflammatory protein Macrophages Neurology NF-κB protein Original Research Paper Pharmacology/Toxicology Phosphorylation Polyinosinic:polycytidylic acid RANTES Respiratory tract Respiratory tract diseases Rheumatology Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!