Toward zonally tailored scaffolds for osteochondral differentiation of synovial mesenchymal stem cells

Synovium‐derived mesenchymal stem cells (SMSCs) are an emerging cell source for regenerative medicine applications, including osteochondral defect (OCD) repair. However, in contrast to bone marrow MSCs, scaffold compositions which promote SMSC chondrogenesis/osteogenesis are still being identified....

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2019-08, Vol.107 (6), p.2019-2029
Hauptverfasser:	Diaz‐Rodriguez, Patricia, Erndt‐Marino, Josh D., Gharat, Tanmay, Munoz Pinto, Dany J., Samavedi, Satyavrata, Bearden, Robert, Grunlan, Melissa A., Saunders, W. Brian, Hahn, Mariah S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggrecan Biocompatibility Biomedical materials Bone marrow Bone morphogenetic protein 2 Chondrocytes Chondrogenesis Collagen Collagen (type X) Differentiation Eutrophication Formulations Glycosaminoglycans Growth factors Hyaluronic acid Knee Materials research Materials science Mesenchymal stem cells Mesenchyme Mineralization Osteoblasts osteochondral tissue Osteogenesis Osteopontin PEG scaffolds Polydimethylsiloxane Regenerative medicine Repair Scaffolds Silicone resins Sox9 protein Stem cells Sulfates Synovium synovium‐derived mesenchymal stem cells Transforming growth factor-b1
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