The QT Scale: A Weight Scale Measuring the QTc Interval
Introduction Despite the strong evidence of the clinical utility of QTc prolongation as a surrogate marker of cardiac risk, QTc measurement is not part of clinical routine either in hospital or in physician offices. We evaluated a novel device (“the QT scale”) to measure heart rate (HR) and QTc inte...
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| Veröffentlicht in: | Annals of noninvasive electrocardiology 2017-01, Vol.22 (1), p.np-n/a |
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| container_title | Annals of noninvasive electrocardiology |
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| creator | Couderc, Jean‐Philippe Beshaw, Connor Niu, Xiaodan Serrano‐Finetti, Ernesto Casas, Oscar Pallas‐Areny, Ramon Rosero, Spencer Zareba, Wojciech |
| description | Introduction
Despite the strong evidence of the clinical utility of QTc prolongation as a surrogate marker of cardiac risk, QTc measurement is not part of clinical routine either in hospital or in physician offices. We evaluated a novel device (“the QT scale”) to measure heart rate (HR) and QTc interval.
Method
The QT scale is a weight scale embedding an ECG acquisition system with four limb sensors (feet and hands: lead I, II, and III). We evaluated the reliability of QT scale in healthy subjects (cohort 1) and cardiac patients (cohorts 2 and 3) considering a learning (cohort 2) and two validation cohorts. The QT scale and the standard 12‐lead recorder were compared using intraclass correlation coefficient (ICC) in cohorts 2 and 3. Absolute value of heart rate and QTc intervals between manual and automatic measurements using ECGs from the QT scale and a clinical device were compared in cohort 1.
Results
We enrolled 16 subjects in cohort 1 (8 w, 8 m; 32 ± 8 vs 34 ± 10 years, P = 0.7), 51 patients in cohort 2 (13 w, 38 m; 61 ± 16 vs 58 ± 18 years, P = 0.6), and 13 AF patients in cohort 3 (4 w, 9 m; 63 ± 10 vs 64 ± 10 years, P = 0.9). Similar automatic heart rate and QTc were delivered by the scale and the clinical device in cohort 1: paired difference in RR and QTc were −7 ± 34 milliseconds (P = 0.37) and 3.4 ± 28.6 milliseconds (P = 0.64), respectively. The measurement of stability was slightly lower in ECG from the QT scale than from the clinical device (ICC: 91% vs 80%) in cohort 3.
Conclusion
The “QT scale device” delivers valid heart rate and QTc interval measurements. |
| doi_str_mv | 10.1111/anec.12378 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6931677</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1859474583</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5528-753f7d482a9937cda608ac761feb234dd3d5ad91af80065421e6d53bc95ab9fe3</originalsourceid><addsrcrecordid>eNqNkVFP2zAQxy3ENBjbCx8AReIFTUqxz3Hs8IBUVbAhAdO0TuPNcp1LG5QmxU5A_fZz2lIGD2iWLPvk3_199z9CDhkdsLBOTY12wIBLtUP2mUggTmRytxvuVEEsgd7tkU_e31MKkID8SPZAJgCp5PtEjmcY_RxHv6yp8CwaRn-wnM7adRzdoPGdK-tp1K4wG13VLbpHU30mHwpTefyyOQ_I78uL8eh7fP3j29VoeB1bIUDFUvBC5okCk2Vc2tykVBkrU1bgBHiS5zwXJs-YKRSlaSidYZoLPrGZMJOsQH5Azte6i24yx9xi3TpT6YUr58YtdWNK_fqlLmd62jzqNOMslTIIsLWA9Z3VDi06a9pV4jboN1AJGhTLOISck82nrnno0Ld6XnqLVRWcbjqvmRJZsFgo_h9o8BkEZUlAj9-g903n6uBeLyikUFT21NdNva7x3mGx7ZVR3Y9b9-PWq3EH-Ohfd7bo83xfun8qK1y-I6WHtxejtehf9j2yWg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1855758074</pqid></control><display><type>article</type><title>The QT Scale: A Weight Scale Measuring the QTc Interval</title><source>Wiley-Blackwell Journals</source><source>MEDLINE</source><source>PubMed (Medline)</source><source>Recercat</source><source>EZB Electronic Journals Library</source><creator>Couderc, Jean‐Philippe ; Beshaw, Connor ; Niu, Xiaodan ; Serrano‐Finetti, Ernesto ; Casas, Oscar ; Pallas‐Areny, Ramon ; Rosero, Spencer ; Zareba, Wojciech</creator><creatorcontrib>Couderc, Jean‐Philippe ; Beshaw, Connor ; Niu, Xiaodan ; Serrano‐Finetti, Ernesto ; Casas, Oscar ; Pallas‐Areny, Ramon ; Rosero, Spencer ; Zareba, Wojciech</creatorcontrib><description>Introduction
Despite the strong evidence of the clinical utility of QTc prolongation as a surrogate marker of cardiac risk, QTc measurement is not part of clinical routine either in hospital or in physician offices. We evaluated a novel device (“the QT scale”) to measure heart rate (HR) and QTc interval.
Method
The QT scale is a weight scale embedding an ECG acquisition system with four limb sensors (feet and hands: lead I, II, and III). We evaluated the reliability of QT scale in healthy subjects (cohort 1) and cardiac patients (cohorts 2 and 3) considering a learning (cohort 2) and two validation cohorts. The QT scale and the standard 12‐lead recorder were compared using intraclass correlation coefficient (ICC) in cohorts 2 and 3. Absolute value of heart rate and QTc intervals between manual and automatic measurements using ECGs from the QT scale and a clinical device were compared in cohort 1.
Results
We enrolled 16 subjects in cohort 1 (8 w, 8 m; 32 ± 8 vs 34 ± 10 years, P = 0.7), 51 patients in cohort 2 (13 w, 38 m; 61 ± 16 vs 58 ± 18 years, P = 0.6), and 13 AF patients in cohort 3 (4 w, 9 m; 63 ± 10 vs 64 ± 10 years, P = 0.9). Similar automatic heart rate and QTc were delivered by the scale and the clinical device in cohort 1: paired difference in RR and QTc were −7 ± 34 milliseconds (P = 0.37) and 3.4 ± 28.6 milliseconds (P = 0.64), respectively. The measurement of stability was slightly lower in ECG from the QT scale than from the clinical device (ICC: 91% vs 80%) in cohort 3.
Conclusion
The “QT scale device” delivers valid heart rate and QTc interval measurements.</description><identifier>ISSN: 1082-720X</identifier><identifier>ISSN: 1542-474X</identifier><identifier>EISSN: 1542-474X</identifier><identifier>DOI: 10.1111/anec.12378</identifier><identifier>PMID: 27422673</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Adult ; Anti-Arrhythmia Agents - therapeutic use ; Atrial Fibrillation - drug therapy ; Atrial Fibrillation - physiopathology ; clinical ; Electrocardiografia ; Electrocardiography ; electrophysiology ; Enginyeria de la telecomunicació ; Female ; Heart Conduction System - physiopathology ; Heart Rate - physiology ; Humans ; long QT syndrome ; Long QT Syndrome - physiopathology ; Male ; Middle Aged ; noninvasive techniques ; Original ; Phenethylamines - therapeutic use ; Sulfonamides - therapeutic use ; Àrees temàtiques de la UPC</subject><ispartof>Annals of noninvasive electrocardiology, 2017-01, Vol.22 (1), p.np-n/a</ispartof><rights>2016 Wiley Periodicals, Inc.</rights><rights>2017 European Society of Cardiology and Wiley Periodicals, Inc.</rights><rights>info:eu-repo/semantics/openAccess</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5528-753f7d482a9937cda608ac761feb234dd3d5ad91af80065421e6d53bc95ab9fe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931677/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931677/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,728,781,785,886,1418,26976,27926,27927,45576,45577,53793,53795</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27422673$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Couderc, Jean‐Philippe</creatorcontrib><creatorcontrib>Beshaw, Connor</creatorcontrib><creatorcontrib>Niu, Xiaodan</creatorcontrib><creatorcontrib>Serrano‐Finetti, Ernesto</creatorcontrib><creatorcontrib>Casas, Oscar</creatorcontrib><creatorcontrib>Pallas‐Areny, Ramon</creatorcontrib><creatorcontrib>Rosero, Spencer</creatorcontrib><creatorcontrib>Zareba, Wojciech</creatorcontrib><title>The QT Scale: A Weight Scale Measuring the QTc Interval</title><title>Annals of noninvasive electrocardiology</title><addtitle>Ann Noninvasive Electrocardiol</addtitle><description>Introduction
Despite the strong evidence of the clinical utility of QTc prolongation as a surrogate marker of cardiac risk, QTc measurement is not part of clinical routine either in hospital or in physician offices. We evaluated a novel device (“the QT scale”) to measure heart rate (HR) and QTc interval.
Method
The QT scale is a weight scale embedding an ECG acquisition system with four limb sensors (feet and hands: lead I, II, and III). We evaluated the reliability of QT scale in healthy subjects (cohort 1) and cardiac patients (cohorts 2 and 3) considering a learning (cohort 2) and two validation cohorts. The QT scale and the standard 12‐lead recorder were compared using intraclass correlation coefficient (ICC) in cohorts 2 and 3. Absolute value of heart rate and QTc intervals between manual and automatic measurements using ECGs from the QT scale and a clinical device were compared in cohort 1.
Results
We enrolled 16 subjects in cohort 1 (8 w, 8 m; 32 ± 8 vs 34 ± 10 years, P = 0.7), 51 patients in cohort 2 (13 w, 38 m; 61 ± 16 vs 58 ± 18 years, P = 0.6), and 13 AF patients in cohort 3 (4 w, 9 m; 63 ± 10 vs 64 ± 10 years, P = 0.9). Similar automatic heart rate and QTc were delivered by the scale and the clinical device in cohort 1: paired difference in RR and QTc were −7 ± 34 milliseconds (P = 0.37) and 3.4 ± 28.6 milliseconds (P = 0.64), respectively. The measurement of stability was slightly lower in ECG from the QT scale than from the clinical device (ICC: 91% vs 80%) in cohort 3.
Conclusion
The “QT scale device” delivers valid heart rate and QTc interval measurements.</description><subject>Adult</subject><subject>Anti-Arrhythmia Agents - therapeutic use</subject><subject>Atrial Fibrillation - drug therapy</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>clinical</subject><subject>Electrocardiografia</subject><subject>Electrocardiography</subject><subject>electrophysiology</subject><subject>Enginyeria de la telecomunicació</subject><subject>Female</subject><subject>Heart Conduction System - physiopathology</subject><subject>Heart Rate - physiology</subject><subject>Humans</subject><subject>long QT syndrome</subject><subject>Long QT Syndrome - physiopathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>noninvasive techniques</subject><subject>Original</subject><subject>Phenethylamines - therapeutic use</subject><subject>Sulfonamides - therapeutic use</subject><subject>Àrees temàtiques de la UPC</subject><issn>1082-720X</issn><issn>1542-474X</issn><issn>1542-474X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>XX2</sourceid><recordid>eNqNkVFP2zAQxy3ENBjbCx8AReIFTUqxz3Hs8IBUVbAhAdO0TuPNcp1LG5QmxU5A_fZz2lIGD2iWLPvk3_199z9CDhkdsLBOTY12wIBLtUP2mUggTmRytxvuVEEsgd7tkU_e31MKkID8SPZAJgCp5PtEjmcY_RxHv6yp8CwaRn-wnM7adRzdoPGdK-tp1K4wG13VLbpHU30mHwpTefyyOQ_I78uL8eh7fP3j29VoeB1bIUDFUvBC5okCk2Vc2tykVBkrU1bgBHiS5zwXJs-YKRSlaSidYZoLPrGZMJOsQH5Azte6i24yx9xi3TpT6YUr58YtdWNK_fqlLmd62jzqNOMslTIIsLWA9Z3VDi06a9pV4jboN1AJGhTLOISck82nrnno0Ld6XnqLVRWcbjqvmRJZsFgo_h9o8BkEZUlAj9-g903n6uBeLyikUFT21NdNva7x3mGx7ZVR3Y9b9-PWq3EH-Ohfd7bo83xfun8qK1y-I6WHtxejtehf9j2yWg</recordid><startdate>201701</startdate><enddate>201701</enddate><creator>Couderc, Jean‐Philippe</creator><creator>Beshaw, Connor</creator><creator>Niu, Xiaodan</creator><creator>Serrano‐Finetti, Ernesto</creator><creator>Casas, Oscar</creator><creator>Pallas‐Areny, Ramon</creator><creator>Rosero, Spencer</creator><creator>Zareba, Wojciech</creator><general>John Wiley & Sons, Inc</general><general>Wiley</general><general>John Wiley and Sons Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope><scope>XX2</scope><scope>5PM</scope></search><sort><creationdate>201701</creationdate><title>The QT Scale: A Weight Scale Measuring the QTc Interval</title><author>Couderc, Jean‐Philippe ; Beshaw, Connor ; Niu, Xiaodan ; Serrano‐Finetti, Ernesto ; Casas, Oscar ; Pallas‐Areny, Ramon ; Rosero, Spencer ; Zareba, Wojciech</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5528-753f7d482a9937cda608ac761feb234dd3d5ad91af80065421e6d53bc95ab9fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Anti-Arrhythmia Agents - therapeutic use</topic><topic>Atrial Fibrillation - drug therapy</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>clinical</topic><topic>Electrocardiografia</topic><topic>Electrocardiography</topic><topic>electrophysiology</topic><topic>Enginyeria de la telecomunicació</topic><topic>Female</topic><topic>Heart Conduction System - physiopathology</topic><topic>Heart Rate - physiology</topic><topic>Humans</topic><topic>long QT syndrome</topic><topic>Long QT Syndrome - physiopathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>noninvasive techniques</topic><topic>Original</topic><topic>Phenethylamines - therapeutic use</topic><topic>Sulfonamides - therapeutic use</topic><topic>Àrees temàtiques de la UPC</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Couderc, Jean‐Philippe</creatorcontrib><creatorcontrib>Beshaw, Connor</creatorcontrib><creatorcontrib>Niu, Xiaodan</creatorcontrib><creatorcontrib>Serrano‐Finetti, Ernesto</creatorcontrib><creatorcontrib>Casas, Oscar</creatorcontrib><creatorcontrib>Pallas‐Areny, Ramon</creatorcontrib><creatorcontrib>Rosero, Spencer</creatorcontrib><creatorcontrib>Zareba, Wojciech</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Recercat</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of noninvasive electrocardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Couderc, Jean‐Philippe</au><au>Beshaw, Connor</au><au>Niu, Xiaodan</au><au>Serrano‐Finetti, Ernesto</au><au>Casas, Oscar</au><au>Pallas‐Areny, Ramon</au><au>Rosero, Spencer</au><au>Zareba, Wojciech</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The QT Scale: A Weight Scale Measuring the QTc Interval</atitle><jtitle>Annals of noninvasive electrocardiology</jtitle><addtitle>Ann Noninvasive Electrocardiol</addtitle><date>2017-01</date><risdate>2017</risdate><volume>22</volume><issue>1</issue><spage>np</spage><epage>n/a</epage><pages>np-n/a</pages><issn>1082-720X</issn><issn>1542-474X</issn><eissn>1542-474X</eissn><abstract>Introduction
Despite the strong evidence of the clinical utility of QTc prolongation as a surrogate marker of cardiac risk, QTc measurement is not part of clinical routine either in hospital or in physician offices. We evaluated a novel device (“the QT scale”) to measure heart rate (HR) and QTc interval.
Method
The QT scale is a weight scale embedding an ECG acquisition system with four limb sensors (feet and hands: lead I, II, and III). We evaluated the reliability of QT scale in healthy subjects (cohort 1) and cardiac patients (cohorts 2 and 3) considering a learning (cohort 2) and two validation cohorts. The QT scale and the standard 12‐lead recorder were compared using intraclass correlation coefficient (ICC) in cohorts 2 and 3. Absolute value of heart rate and QTc intervals between manual and automatic measurements using ECGs from the QT scale and a clinical device were compared in cohort 1.
Results
We enrolled 16 subjects in cohort 1 (8 w, 8 m; 32 ± 8 vs 34 ± 10 years, P = 0.7), 51 patients in cohort 2 (13 w, 38 m; 61 ± 16 vs 58 ± 18 years, P = 0.6), and 13 AF patients in cohort 3 (4 w, 9 m; 63 ± 10 vs 64 ± 10 years, P = 0.9). Similar automatic heart rate and QTc were delivered by the scale and the clinical device in cohort 1: paired difference in RR and QTc were −7 ± 34 milliseconds (P = 0.37) and 3.4 ± 28.6 milliseconds (P = 0.64), respectively. The measurement of stability was slightly lower in ECG from the QT scale than from the clinical device (ICC: 91% vs 80%) in cohort 3.
Conclusion
The “QT scale device” delivers valid heart rate and QTc interval measurements.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>27422673</pmid><doi>10.1111/anec.12378</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| source | Wiley-Blackwell Journals; MEDLINE; PubMed (Medline); Recercat; EZB Electronic Journals Library |
| subjects | Adult Anti-Arrhythmia Agents - therapeutic use Atrial Fibrillation - drug therapy Atrial Fibrillation - physiopathology clinical Electrocardiografia Electrocardiography electrophysiology Enginyeria de la telecomunicació Female Heart Conduction System - physiopathology Heart Rate - physiology Humans long QT syndrome Long QT Syndrome - physiopathology Male Middle Aged noninvasive techniques Original Phenethylamines - therapeutic use Sulfonamides - therapeutic use Àrees temàtiques de la UPC |
| title | The QT Scale: A Weight Scale Measuring the QTc Interval |
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