The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome
Background and aim New‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac eve...
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| Veröffentlicht in: | Annals of noninvasive electrocardiology 2019-07, Vol.24 (4), p.e12622-n/a |
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| creator | Cirakoglu, Omer Faruk Aslan, Ahmet Oğuz Akyuz, Ali Riza Kul, Selim Şahin, Sinan Korkmaz, Levent Sayın, Muhammet Raşit |
| description | Background and aim
New‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac events. In this study, we aimed to assess the relationship between SS and NOAF with known predictors of atrial fibrillation.
Methods
In a prospective, single‐center, cross‐sectional study, 692 patients who were diagnosed with coronary artery disease for the first time were enrolled consecutively. NOAF was defined as atrial fibrillation, which was documented after hospital admission. SS was calculated by a computer software. Multivariable logistic regression analyzes were used to detect the relationship between variables and NOAF.
Results
New‐onset atrial fibrillation was detected in 82 patients (11.8%). Patients with NOAF had higher SS (22, interquartile range 18.3–25.1, vs. 12, interquartile range 7–19.5, p |
| doi_str_mv | 10.1111/anec.12622 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6931656</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2258052938</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4482-bd129d44929b85cc4e2fb68084ec1c9bd7ac64f1b2cc0bd6590e4f2a6b306c083</originalsourceid><addsrcrecordid>eNp9kdFqFDEUhoMotlZvfIAS8EaErcmZTHbmRihLtULRmwq9C0nmjJsyk2yTTNe96yP0GX0Ss91aWi_MTQ7k4-M_-Ql5y9kRL-ej9miPOEiAZ2Sf1wJmYi4unpeZNTCbA7vYI69SumQMQMD8JdmrmOQ1VHKfjOdLpNd6mJCGnqaNz_oXTTZEpDnQVcTO2Uw9rn_f3AafMFOdo9MD7Z2Jbhh0dsFT5-mqTOhzomuXl1TbKSMtmuB13Gy9XQwjviYvej0kfHN_H5Afn0_OF6ezs-9fvi6Oz2ZWiBLZdBzaTogWWtPU1gqE3siGNQItt63p5tpK0XMD1jLTybplKHrQ0pTFLGuqA_Jp511NZsTOlmBRD2oV3VjiqKCdevri3VL9DNdKthWXtSyC9_eCGK4mTFmNLlks-3oMU1LApajLL0tW0Hf_oJdhir6spwDqhtXQVttEH3aUjSGliP1DGM7UtkW1bVHdtVjgw8fxH9C_tRWA74C1G3DzH5U6_nay2En_ABJFqzo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2258052938</pqid></control><display><type>article</type><title>The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Cirakoglu, Omer Faruk ; Aslan, Ahmet Oğuz ; Akyuz, Ali Riza ; Kul, Selim ; Şahin, Sinan ; Korkmaz, Levent ; Sayın, Muhammet Raşit</creator><creatorcontrib>Cirakoglu, Omer Faruk ; Aslan, Ahmet Oğuz ; Akyuz, Ali Riza ; Kul, Selim ; Şahin, Sinan ; Korkmaz, Levent ; Sayın, Muhammet Raşit</creatorcontrib><description>Background and aim
New‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac events. In this study, we aimed to assess the relationship between SS and NOAF with known predictors of atrial fibrillation.
Methods
In a prospective, single‐center, cross‐sectional study, 692 patients who were diagnosed with coronary artery disease for the first time were enrolled consecutively. NOAF was defined as atrial fibrillation, which was documented after hospital admission. SS was calculated by a computer software. Multivariable logistic regression analyzes were used to detect the relationship between variables and NOAF.
Results
New‐onset atrial fibrillation was detected in 82 patients (11.8%). Patients with NOAF had higher SS (22, interquartile range 18.3–25.1, vs. 12, interquartile range 7–19.5, p < 0.001). According to multivariable logistic regression analysis for NOAF, SS were independently and significantly associated (OR, 1.103; 95% confidence interval, 1.047–1.163; p < 0.001). Other independent predictors of NOAF were TIMI flow <3, C reactive protein, left ventricular ejection fraction, left atrial volume index and E/E′ ratio. The optimal cut‐off value for SS was 18 for the development of NOAF with 82% sensitivity and 68% specificity (area under the curve: 0.795, 95% confidence interval 0.749–0.841, p < 0.001).
Conclusion
Syntax score may be helpful to identify for patients who would develop atrial fibrillation in the setting of ACS.</description><identifier>ISSN: 1082-720X</identifier><identifier>EISSN: 1542-474X</identifier><identifier>DOI: 10.1111/anec.12622</identifier><identifier>PMID: 30615236</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>acute coronary syndrome ; Acute Coronary Syndrome - complications ; Acute coronary syndromes ; Atrial Fibrillation - complications ; Atrial Fibrillation - diagnosis ; C-reactive protein ; Cardiac arrhythmia ; Cardiovascular disease ; Confidence intervals ; Coronary artery ; Coronary artery disease ; Cross-Sectional Studies ; Electrocardiography ; Electrocardiography - methods ; Female ; Fibrillation ; Heart ; Heart diseases ; Humans ; Male ; Middle Aged ; new‐onset atrial fibrillation ; Original ; Prospective Studies ; Regression analysis ; Statistical analysis ; Syntax ; SYNTAX Score ; Ventricle</subject><ispartof>Annals of noninvasive electrocardiology, 2019-07, Vol.24 (4), p.e12622-n/a</ispartof><rights>2019 Wiley Periodicals, Inc.</rights><rights>2019 European Society of Cardiology and Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4482-bd129d44929b85cc4e2fb68084ec1c9bd7ac64f1b2cc0bd6590e4f2a6b306c083</citedby><cites>FETCH-LOGICAL-c4482-bd129d44929b85cc4e2fb68084ec1c9bd7ac64f1b2cc0bd6590e4f2a6b306c083</cites><orcidid>0000-0003-3327-7850 ; 0000-0001-8329-4603 ; 0000-0002-1815-437X ; 0000-0002-3687-0580 ; 0000-0002-2306-9954 ; 0000-0002-6991-5749</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931656/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931656/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,1411,27901,27902,45550,45551,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30615236$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cirakoglu, Omer Faruk</creatorcontrib><creatorcontrib>Aslan, Ahmet Oğuz</creatorcontrib><creatorcontrib>Akyuz, Ali Riza</creatorcontrib><creatorcontrib>Kul, Selim</creatorcontrib><creatorcontrib>Şahin, Sinan</creatorcontrib><creatorcontrib>Korkmaz, Levent</creatorcontrib><creatorcontrib>Sayın, Muhammet Raşit</creatorcontrib><title>The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome</title><title>Annals of noninvasive electrocardiology</title><addtitle>Ann Noninvasive Electrocardiol</addtitle><description>Background and aim
New‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac events. In this study, we aimed to assess the relationship between SS and NOAF with known predictors of atrial fibrillation.
Methods
In a prospective, single‐center, cross‐sectional study, 692 patients who were diagnosed with coronary artery disease for the first time were enrolled consecutively. NOAF was defined as atrial fibrillation, which was documented after hospital admission. SS was calculated by a computer software. Multivariable logistic regression analyzes were used to detect the relationship between variables and NOAF.
Results
New‐onset atrial fibrillation was detected in 82 patients (11.8%). Patients with NOAF had higher SS (22, interquartile range 18.3–25.1, vs. 12, interquartile range 7–19.5, p < 0.001). According to multivariable logistic regression analysis for NOAF, SS were independently and significantly associated (OR, 1.103; 95% confidence interval, 1.047–1.163; p < 0.001). Other independent predictors of NOAF were TIMI flow <3, C reactive protein, left ventricular ejection fraction, left atrial volume index and E/E′ ratio. The optimal cut‐off value for SS was 18 for the development of NOAF with 82% sensitivity and 68% specificity (area under the curve: 0.795, 95% confidence interval 0.749–0.841, p < 0.001).
Conclusion
Syntax score may be helpful to identify for patients who would develop atrial fibrillation in the setting of ACS.</description><subject>acute coronary syndrome</subject><subject>Acute Coronary Syndrome - complications</subject><subject>Acute coronary syndromes</subject><subject>Atrial Fibrillation - complications</subject><subject>Atrial Fibrillation - diagnosis</subject><subject>C-reactive protein</subject><subject>Cardiac arrhythmia</subject><subject>Cardiovascular disease</subject><subject>Confidence intervals</subject><subject>Coronary artery</subject><subject>Coronary artery disease</subject><subject>Cross-Sectional Studies</subject><subject>Electrocardiography</subject><subject>Electrocardiography - methods</subject><subject>Female</subject><subject>Fibrillation</subject><subject>Heart</subject><subject>Heart diseases</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>new‐onset atrial fibrillation</subject><subject>Original</subject><subject>Prospective Studies</subject><subject>Regression analysis</subject><subject>Statistical analysis</subject><subject>Syntax</subject><subject>SYNTAX Score</subject><subject>Ventricle</subject><issn>1082-720X</issn><issn>1542-474X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kdFqFDEUhoMotlZvfIAS8EaErcmZTHbmRihLtULRmwq9C0nmjJsyk2yTTNe96yP0GX0Ss91aWi_MTQ7k4-M_-Ql5y9kRL-ej9miPOEiAZ2Sf1wJmYi4unpeZNTCbA7vYI69SumQMQMD8JdmrmOQ1VHKfjOdLpNd6mJCGnqaNz_oXTTZEpDnQVcTO2Uw9rn_f3AafMFOdo9MD7Z2Jbhh0dsFT5-mqTOhzomuXl1TbKSMtmuB13Gy9XQwjviYvej0kfHN_H5Afn0_OF6ezs-9fvi6Oz2ZWiBLZdBzaTogWWtPU1gqE3siGNQItt63p5tpK0XMD1jLTybplKHrQ0pTFLGuqA_Jp511NZsTOlmBRD2oV3VjiqKCdevri3VL9DNdKthWXtSyC9_eCGK4mTFmNLlks-3oMU1LApajLL0tW0Hf_oJdhir6spwDqhtXQVttEH3aUjSGliP1DGM7UtkW1bVHdtVjgw8fxH9C_tRWA74C1G3DzH5U6_nay2En_ABJFqzo</recordid><startdate>201907</startdate><enddate>201907</enddate><creator>Cirakoglu, Omer Faruk</creator><creator>Aslan, Ahmet Oğuz</creator><creator>Akyuz, Ali Riza</creator><creator>Kul, Selim</creator><creator>Şahin, Sinan</creator><creator>Korkmaz, Levent</creator><creator>Sayın, Muhammet Raşit</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-3327-7850</orcidid><orcidid>https://orcid.org/0000-0001-8329-4603</orcidid><orcidid>https://orcid.org/0000-0002-1815-437X</orcidid><orcidid>https://orcid.org/0000-0002-3687-0580</orcidid><orcidid>https://orcid.org/0000-0002-2306-9954</orcidid><orcidid>https://orcid.org/0000-0002-6991-5749</orcidid></search><sort><creationdate>201907</creationdate><title>The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome</title><author>Cirakoglu, Omer Faruk ; Aslan, Ahmet Oğuz ; Akyuz, Ali Riza ; Kul, Selim ; Şahin, Sinan ; Korkmaz, Levent ; Sayın, Muhammet Raşit</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4482-bd129d44929b85cc4e2fb68084ec1c9bd7ac64f1b2cc0bd6590e4f2a6b306c083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>acute coronary syndrome</topic><topic>Acute Coronary Syndrome - complications</topic><topic>Acute coronary syndromes</topic><topic>Atrial Fibrillation - complications</topic><topic>Atrial Fibrillation - diagnosis</topic><topic>C-reactive protein</topic><topic>Cardiac arrhythmia</topic><topic>Cardiovascular disease</topic><topic>Confidence intervals</topic><topic>Coronary artery</topic><topic>Coronary artery disease</topic><topic>Cross-Sectional Studies</topic><topic>Electrocardiography</topic><topic>Electrocardiography - methods</topic><topic>Female</topic><topic>Fibrillation</topic><topic>Heart</topic><topic>Heart diseases</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>new‐onset atrial fibrillation</topic><topic>Original</topic><topic>Prospective Studies</topic><topic>Regression analysis</topic><topic>Statistical analysis</topic><topic>Syntax</topic><topic>SYNTAX Score</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cirakoglu, Omer Faruk</creatorcontrib><creatorcontrib>Aslan, Ahmet Oğuz</creatorcontrib><creatorcontrib>Akyuz, Ali Riza</creatorcontrib><creatorcontrib>Kul, Selim</creatorcontrib><creatorcontrib>Şahin, Sinan</creatorcontrib><creatorcontrib>Korkmaz, Levent</creatorcontrib><creatorcontrib>Sayın, Muhammet Raşit</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of noninvasive electrocardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cirakoglu, Omer Faruk</au><au>Aslan, Ahmet Oğuz</au><au>Akyuz, Ali Riza</au><au>Kul, Selim</au><au>Şahin, Sinan</au><au>Korkmaz, Levent</au><au>Sayın, Muhammet Raşit</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome</atitle><jtitle>Annals of noninvasive electrocardiology</jtitle><addtitle>Ann Noninvasive Electrocardiol</addtitle><date>2019-07</date><risdate>2019</risdate><volume>24</volume><issue>4</issue><spage>e12622</spage><epage>n/a</epage><pages>e12622-n/a</pages><issn>1082-720X</issn><eissn>1542-474X</eissn><abstract>Background and aim
New‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac events. In this study, we aimed to assess the relationship between SS and NOAF with known predictors of atrial fibrillation.
Methods
In a prospective, single‐center, cross‐sectional study, 692 patients who were diagnosed with coronary artery disease for the first time were enrolled consecutively. NOAF was defined as atrial fibrillation, which was documented after hospital admission. SS was calculated by a computer software. Multivariable logistic regression analyzes were used to detect the relationship between variables and NOAF.
Results
New‐onset atrial fibrillation was detected in 82 patients (11.8%). Patients with NOAF had higher SS (22, interquartile range 18.3–25.1, vs. 12, interquartile range 7–19.5, p < 0.001). According to multivariable logistic regression analysis for NOAF, SS were independently and significantly associated (OR, 1.103; 95% confidence interval, 1.047–1.163; p < 0.001). Other independent predictors of NOAF were TIMI flow <3, C reactive protein, left ventricular ejection fraction, left atrial volume index and E/E′ ratio. The optimal cut‐off value for SS was 18 for the development of NOAF with 82% sensitivity and 68% specificity (area under the curve: 0.795, 95% confidence interval 0.749–0.841, p < 0.001).
Conclusion
Syntax score may be helpful to identify for patients who would develop atrial fibrillation in the setting of ACS.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>30615236</pmid><doi>10.1111/anec.12622</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-3327-7850</orcidid><orcidid>https://orcid.org/0000-0001-8329-4603</orcidid><orcidid>https://orcid.org/0000-0002-1815-437X</orcidid><orcidid>https://orcid.org/0000-0002-3687-0580</orcidid><orcidid>https://orcid.org/0000-0002-2306-9954</orcidid><orcidid>https://orcid.org/0000-0002-6991-5749</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | acute coronary syndrome Acute Coronary Syndrome - complications Acute coronary syndromes Atrial Fibrillation - complications Atrial Fibrillation - diagnosis C-reactive protein Cardiac arrhythmia Cardiovascular disease Confidence intervals Coronary artery Coronary artery disease Cross-Sectional Studies Electrocardiography Electrocardiography - methods Female Fibrillation Heart Heart diseases Humans Male Middle Aged new‐onset atrial fibrillation Original Prospective Studies Regression analysis Statistical analysis Syntax SYNTAX Score Ventricle |
| title | The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome |
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