Engineering geometrical 3-dimensional untethered in vitro neural tissue mimic

Formation of tissue models in 3 dimensions is more effective in recapitulating structure and function compared to their 2-dimensional (2D) counterparts. Formation of 3D engineered tissue to control shape and size can have important implications in biomedical research and in engineering applications...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2019-12, Vol.116 (51), p.25932-25940
Hauptverfasser:	Pagan-Diaz, Gelson J., Ramos-Cruz, Karla P., Sam, Richard, Kandel, Mikhail E., Aydin, Onur, Saif, M. Taher A., Popescu, Gabriel, Bashir, Rashid
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Biomedical engineering Biomedical research Cells, Cultured Construction Embryo cells Embryonic Stem Cells - cytology Embryos Extracellular matrix Fibrin Humans Mice Nerve Tissue - cytology Physical Sciences Robotics Spheroids Spheroids, Cellular - cytology Stem cell transplantation Stem cells Structure-function relationships Three dimensional models Three dimensional printing Tissue Culture Techniques - methods Tissue Engineering - methods Tissue Scaffolds Tissues
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