Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

Maternal gestational diabetes mellitus (GDM) has been associated with adverse outcomes in the offspring. Growing evidence suggests that the epigenome may play a role, but most previous studies have been small and adjusted for few covariates. The current study meta-analyzed the association between ma...

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Veröffentlicht in:	Diabetes care 2020-01, Vol.43 (1), p.98-105
Hauptverfasser:	Howe, Caitlin G, Cox, Bianca, Fore, Ruby, Jungius, James, Kvist, Tuomas, Lent, Samantha, Miles, Harriet E, Salas, Lucas A, Rifas-Shiman, Sheryl, Starling, Anne P, Yousefi, Paul, Ladd-Acosta, Christine, Baccarelli, Andrea, Binder, Elisabeth B, Chatzi, Vaia Lida, Czamara, Darina, Dabelea, Dana, DeMeo, Dawn L, Ghantous, Akram, Herceg, Zdenko, Kajantie, Eero, Lahti, Jari M T, Lawlor, Debbie A, Litonjua, Augusto, Nawrot, Tim S, Nohr, Ellen A, Oken, Emily, Pizzi, Costanza, Plusquin, Michelle, Räikkönen, Katri, Relton, Caroline L, Sharp, Gemma C, Sørensen, Thorkild I A, Sunyer, Jordi, Vrijheid, Martine, Zhang, Weiming, Hivert, Marie-France, Breton, Carrie V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Autism Autism Spectrum Disorder - epidemiology Autism Spectrum Disorder - genetics Blood Case-Control Studies Child Children Cohort Studies Consortia Cord blood Data acquisition Deoxyribonucleic acid Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Diabetes, Gestational - epidemiology DNA DNA Methylation Epidemiology/Health Services Research Epigenesis, Genetic - physiology Epigenetics Epigenome - physiology Female Fetal Blood - metabolism Genome-Wide Association Study Gestational diabetes Humans Infant, Newborn Male Neonates Newborn babies Offspring Pregnancy Prenatal Exposure Delayed Effects - genetics Regression analysis Research design Robustness (mathematics) Young Adult
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