MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2

Osteosarcoma (OS) is the most common form of bone malignancy in children and adolescents. MicroRNAs (miRNAs) have been associated with the development and progression of OS. In the present study, reverse transcription-quantitative PCR, western blotting, Cell Counting Kit-8, luciferase and Transwell...

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Veröffentlicht in:	Experimental and therapeutic medicine 2020-01, Vol.19 (1), p.481-488
Hauptverfasser:	Ling, Zhonghua, Fan, Gentao, Yao, Danhua, Zhao, Jianning, Zhou, Yinhua, Feng, Jinzhu, Zhou, Guangxin, Chen, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anthracyclines Apoptosis Biomarkers Biotechnology Bone cancer Cancer Cancer prevention Cancer therapies Cancer treatment Cell growth Chemotherapy Gene expression Genes Immunoglobulins Laboratories Luciferase MicroRNA MicroRNAs Novels Osteosarcoma Plasmids Polymerase chain reaction Sarcoma Scientific equipment industry Software Transcription (Genetics) Tumors Youth
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