Considering B7-CD28 as a family through sequence and structure

With the emergence of immuno-oncology, new therapeutic agents that modulate immune activation and regulation are being used to treat cancer patients with durable response. It is well known that following T-cell receptor (TCR) activation, many co-receptors can augment or suppress the TCR signal, and...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 2019-12, Vol.244 (17), p.1577-1583
Hauptverfasser: West, Sean M, Deng, Xiaodi A
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Sprache:eng
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