Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings

Adeno-associated viral (AAV) vectors have shown great promise in gene delivery as evidenced by recent FDA approvals. Despite efforts to optimize manufacturing for good manufacturing practice (GMP) productions, few academic laboratories have the resources to assess vector composition. One critical co...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Human gene therapy. Part B. Methods 2019-12, Vol.30 (6), p.195-205
Hauptverfasser:	Maynard, Lucy H, Smith, Olivia, Tilmans, Nicolas P, Tham, Eleonore, Hosseinzadeh, Shayan, Tan, Weilun, Leenay, Ryan, May, Andrew P, Paulk, Nicole K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dependovirus - genetics Dependovirus - physiology DNA, Single-Stranded - chemistry DNA, Single-Stranded - metabolism DNA, Viral - chemistry DNA, Viral - metabolism HEK293 Cells Humans Protocol Sequence Analysis, DNA - methods Sf9 Cells Spodoptera Transposases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!