Eosinophillic Myocarditis Secondary to Metastatic Melanoma

Eosinophilic myocarditis is a rare form of myocarditis that may manifest from cancer-mediated inflammation. A case of eosinophilic myocarditis secondary to metastatic melanoma is described; metastatic melanoma can cause a T helper type 2 lymphocyte-mediated increase in circulating levels of interleu...

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Veröffentlicht in:Radiology. Cardiothoracic imaging 2019-10, Vol.1 (4), p.e190076
Hauptverfasser: Bryde, Robyn E, Ray, Jordan C, Sacco, Keith A, Shapiro, Brian, Cooper, Leslie
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container_title Radiology. Cardiothoracic imaging
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creator Bryde, Robyn E
Ray, Jordan C
Sacco, Keith A
Shapiro, Brian
Cooper, Leslie
description Eosinophilic myocarditis is a rare form of myocarditis that may manifest from cancer-mediated inflammation. A case of eosinophilic myocarditis secondary to metastatic melanoma is described; metastatic melanoma can cause a T helper type 2 lymphocyte-mediated increase in circulating levels of interleukin-5, which is known to stimulate eosinophil proliferation resulting in myocardial inflammation and fibrosis. Cardiac imaging with transesophageal echocardiography revealed a large immobile left ventricular apical thrombus. Cardiac MRI was then performed and revealed enhancing fibrosis along the endocardial surface. © RSNA, 2019 Supplemental material is available for this article.
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title Eosinophillic Myocarditis Secondary to Metastatic Melanoma
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