Immediate reconstruction of mandibular defect after treatment of medication-related osteonecrosis of the jaw (MRONJ) with rhBMP-2/ACS and miniplate: Review of 3 cases
•The pathogenesis of MRONJ is related to repression of osteoclast mediated bone remodeling.•rhBMP-2 can stimulate not only osteoblasts but also osteoclasts and induce new bone formation.•ACS has been proved to be a good carrier of rhBMP-2 with maximal efficacy.•Application of rhBMP-2/ACS can be a ne...
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Veröffentlicht in: | International journal of surgery case reports 2020-01, Vol.66, p.25-29 |
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Sprache: | eng |
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