Immediate reconstruction of mandibular defect after treatment of medication-related osteonecrosis of the jaw (MRONJ) with rhBMP-2/ACS and miniplate: Review of 3 cases

•The pathogenesis of MRONJ is related to repression of osteoclast mediated bone remodeling.•rhBMP-2 can stimulate not only osteoblasts but also osteoclasts and induce new bone formation.•ACS has been proved to be a good carrier of rhBMP-2 with maximal efficacy.•Application of rhBMP-2/ACS can be a ne...

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Veröffentlicht in:International journal of surgery case reports 2020-01, Vol.66, p.25-29
Hauptverfasser: Kim, Mu-seong, Kim, Kyung-jin, Kim, Bok-joo, Kim, Chul-hoon, Kim, Jung-han
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Sprache:eng
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