Analysis of genes linked to depressive-like behaviors in interleukin-18-deficient mice: Gene expression profiles in the brain

Interleukin (IL)-18 is an interferon γ-inducing inflammatory cytokine associated with function of the immune system and other physiological functions. IL-18-deficient ( ) mice exhibit obesity, dyslipidemia, non-alcoholic steatohepatitis and depressive-like behavioral changes. Therefore, IL-18 has a...

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Veröffentlicht in:	Biomedical reports 2020-01, Vol.12 (1), p.3-10
Hauptverfasser:	Yamanishi, Kyosuke, Hashimoto, Takuya, Miyauchi, Masahiro, Mukai, Keiichiro, Ikubo, Kaoru, Uwa, Noriko, Watanabe, Yuko, Ikawa, Takashi, Okuzaki, Daisuke, Okamura, Haruki, Yamanishi, Hiromichi, Matsunaga, Hisato
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Analysis Apoptosis Aquaporins Behavior Biochemistry Biological response modifiers Brain Correlation analysis Cyclin D1 Cytokines Depression (Mood disorder) Disabilities DNA microarrays Dyslipidemia Energy balance Fibroblast growth factor receptor 1 Fibroblast growth factors Fibroblasts Gene expression Genes Genetic aspects Genomes Genomics Growth factors Health maintenance organizations Homeostasis House mouse Immune system Immunology Inflammation Interferon Interferon gamma Interleukin 1 Interleukin 18 Interleukins International economic relations Kinases Laboratory animals Major depressive disorder Medical schools Mental depression Mental disorders NAD(P)H oxidase Nervous system NOX4 protein Obesity Oxidases Phenols (Class of compounds) Phosphatase Phosphatases Polymerase chain reaction Protein-tyrosine-phosphatase Proteins Reverse transcription Tumor necrosis factor-TNF Type 2 diabetes Tyrosine Urocortin γ-Interferon
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