Remineralization Potential of Theobromine on Artificial Carious Lesions
This study aimed to investigate the remineralization potential of two concentrations of theobromine (100 mg/L and 200 mmg/L) with fluoridated dentifrice, NovaMin, and nanohydroxyapatite using DIAGNOdent, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis. Two sections wer...
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| Veröffentlicht in: | Journal of International Society of Preventive & Community Dentistry 2019-11, Vol.9 (6), p.576-583 |
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| description | This study aimed to investigate the remineralization potential of two concentrations of theobromine (100 mg/L and 200 mmg/L) with fluoridated dentifrice, NovaMin, and nanohydroxyapatite using DIAGNOdent, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis.
Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (Colgate™, Colgate -Palmolive, India), Novamine- Shy NM™, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin Pro™, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classic™, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX.
A Tukey
test revealed statistically significant difference between NovaMin and all the other toothpastes (
< 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found.
Theobromine can be used as an effective novel remineralizing agent alternative to the already-available agents. |
| doi_str_mv | 10.4103/jispcd.JISPCD_265_19 |
| format | Article |
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Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (Colgate™, Colgate -Palmolive, India), Novamine- Shy NM™, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin Pro™, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classic™, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX.
A Tukey
test revealed statistically significant difference between NovaMin and all the other toothpastes (
< 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found.
Theobromine can be used as an effective novel remineralizing agent alternative to the already-available agents.</description><identifier>ISSN: 2231-0762</identifier><identifier>EISSN: 2250-1002</identifier><identifier>DOI: 10.4103/jispcd.JISPCD_265_19</identifier><identifier>PMID: 32039078</identifier><language>eng</language><publisher>India: Medknow Publications & Media Pvt. Ltd</publisher><subject>Cavitation ; Dental caries ; Dentifrices ; Dentistry ; Enamel ; Fluoride treatments ; Fluorides ; Hydroxyapatite ; Morphology ; Original ; Remineralization ; Scanning electron microscopy ; Statistical analysis ; Studies ; Teeth</subject><ispartof>Journal of International Society of Preventive & Community Dentistry, 2019-11, Vol.9 (6), p.576-583</ispartof><rights>Copyright: © 2019 Journal of International Society of Preventive and Community Dentistry.</rights><rights>2019. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2019 Journal of International Society of Preventive and Community Dentistry 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-7167142faa27cfe50f2ba75ce48a39da8263b537c2d3cfd26ab66c42168f2fed3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905311/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905311/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,883,27907,27908,53774,53776</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32039078$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taneja, Vani</creatorcontrib><creatorcontrib>Nekkanti, Sridhar</creatorcontrib><creatorcontrib>Gupta, Kanishk</creatorcontrib><creatorcontrib>Hassija, Jyoti</creatorcontrib><title>Remineralization Potential of Theobromine on Artificial Carious Lesions</title><title>Journal of International Society of Preventive & Community Dentistry</title><addtitle>J Int Soc Prev Community Dent</addtitle><description>This study aimed to investigate the remineralization potential of two concentrations of theobromine (100 mg/L and 200 mmg/L) with fluoridated dentifrice, NovaMin, and nanohydroxyapatite using DIAGNOdent, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis.
Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (Colgate™, Colgate -Palmolive, India), Novamine- Shy NM™, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin Pro™, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classic™, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX.
A Tukey
test revealed statistically significant difference between NovaMin and all the other toothpastes (
< 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found.
Theobromine can be used as an effective novel remineralizing agent alternative to the already-available agents.</description><subject>Cavitation</subject><subject>Dental caries</subject><subject>Dentifrices</subject><subject>Dentistry</subject><subject>Enamel</subject><subject>Fluoride treatments</subject><subject>Fluorides</subject><subject>Hydroxyapatite</subject><subject>Morphology</subject><subject>Original</subject><subject>Remineralization</subject><subject>Scanning electron microscopy</subject><subject>Statistical analysis</subject><subject>Studies</subject><subject>Teeth</subject><issn>2231-0762</issn><issn>2250-1002</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpVUV1LwzAUDaK4MfcPRAo-d-ajTdoXYdQ5JwOHzueQponL2JqZtIL-elM2h7svuXA-crgHgGsERwmC5G5t_E5Wo-fZ26J44JimHOVnoI9xCmMEIT7vdoJiyCjugaH3axiGZknO6CXoEQxJDlnWB9NXtTW1cmJjfkRjbB0tbKPqxohNZHW0XClbOttRooCNXWO0kR1YCGds66O58kHlr8CFFhuvhod3AN4fJ8viKZ6_TGfFeB7LhNAmZogylGAtBGZSqxRqXAqWSpVkguSVyDAlZUqYxBWRusJUlJTKBCOaaaxVRQbgfu-7a8utqmSIGrLznTNb4b65FYafIrVZ8Q_7xWkOU4JQMLg9GDj72Srf8LVtXR0y83CwHKEsox0r2bOks947pY8_IMi7Bvi-AX7SQJDd_E93FP3dm_wC6gWGVQ</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Taneja, Vani</creator><creator>Nekkanti, Sridhar</creator><creator>Gupta, Kanishk</creator><creator>Hassija, Jyoti</creator><general>Medknow Publications & Media Pvt. 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Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (Colgate™, Colgate -Palmolive, India), Novamine- Shy NM™, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin Pro™, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classic™, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX.
A Tukey
test revealed statistically significant difference between NovaMin and all the other toothpastes (
< 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found.
Theobromine can be used as an effective novel remineralizing agent alternative to the already-available agents.</abstract><cop>India</cop><pub>Medknow Publications & Media Pvt. Ltd</pub><pmid>32039078</pmid><doi>10.4103/jispcd.JISPCD_265_19</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Cavitation Dental caries Dentifrices Dentistry Enamel Fluoride treatments Fluorides Hydroxyapatite Morphology Original Remineralization Scanning electron microscopy Statistical analysis Studies Teeth |
| title | Remineralization Potential of Theobromine on Artificial Carious Lesions |
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