Two‐way crosstalk between BER and c‐NHEJ repair pathway is mediated by Pol‐β and Ku70

Multiple DNA repair pathways may be involved in the removal of the same DNA lesion caused by endogenous or exogenous agents. Although distinct DNA repair machinery fulfill overlapping roles in the repair of DNA lesions, the mechanisms coordinating different pathways have not been investigated in det...

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Veröffentlicht in:	The FASEB journal 2019-11, Vol.33 (11), p.11668-11681
Hauptverfasser:	Xia, Wen, Ci, Shusheng, Li, Menghan, Wang, Meina, Dianov, Grigory L., Ma, Zhuang, Li, Lulu, Hua, Ke, Alagamuthu, Karthick Kumar, Qing, Lihong, Luo, Libo, Edick, Ashlin M., Liu, Lingjie, Hu, Zhigang, He, Lingfeng, Pan, Feiyan, Guo, Zhigang
Format:	Artikel
Sprache:	eng
Schlagworte:	base excision repair DNA - metabolism DNA Breaks, Double-Stranded DNA Damage - genetics DNA Polymerase beta - genetics DNA repair DNA Repair - genetics DNA Replication - genetics DNA-Binding Proteins - metabolism double‐strand break Humans Ku Autoantigen - metabolism
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