Protein tyrosine phosphatase 11 acts through RhoA/ROCK to regulate eosinophil accumulation in the allergic airway

Src homology domain 2‐containing protein tyrosine phosphatase 2 (SHP2) participates in multiple cell functions including cell shape, movement, and differentiation. Therefore, we investigated the potential role of SHP2 in eosinophil recruitment into lungs in allergic airway inflammation and explored...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The FASEB journal 2019-11, Vol.33 (11), p.11706-11720
Hauptverfasser:	Xu, Chengyun, Wu, Xiling, Lu, Meiping, Tang, Lanfang, Yao, Hongyi, Wang, Jirong, Ji, Xing, Hussain, Musaddique, Wu, Junsong, Wu, Ximei
Format:	Artikel
Sprache:	eng
Schlagworte:	airway inflammation Allergens - immunology Allergens - metabolism Animals asthma Asthma - metabolism Cell Differentiation - immunology cell migration Disease Models, Animal Eosinophils - immunology Eosinophils - metabolism Female Humans Hypersensitivity - metabolism Inflammation - immunology Inflammation - metabolism Lung - metabolism Male Mice Mice, Inbred C57BL Rats, Sprague-Dawley rho-Associated Kinases - metabolism rhoA GTP-Binding Protein - metabolism SHP2
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!