Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques

Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions and extracellular interactions that are biologic...

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Veröffentlicht in:	Scientific reports 2019-12, Vol.9 (1), p.18585-18, Article 18585
Hauptverfasser:	Sitiwin, Ephrem, Madigan, Michele C., Gratton, Enrico, Cherepanoff, Svetlana, Conway, Robert Max, Whan, Renee, Macmillan, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	14/63 14/69 631/57/2267 631/67/1484 631/67/2321 639/624/1107/328/2057 Aged Cell migration Choroid - chemistry Cytoplasm - chemistry Emissions Female Fluorophores Fundus Oculi Gene expression Hair HEK293 Cells Humanities and Social Sciences Humans Image processing Immune response Lifetime Light Male Melanin Melanins - chemistry Melanocytes Melanocytes - chemistry Melanoma - chemistry Melanosomes Melanosomes - chemistry Microscopy Microscopy - methods Middle Aged multidisciplinary NAD - chemistry Neural crest Pheomelanin Photons Physiology Pigmentation Science Science (multidisciplinary) Scientific imaging Segmentation Skin Skin Neoplasms - chemistry Spatial distribution Uvea
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