Characterization of NCS1–InsP3R1 interaction and its functional significance

Inositol 1,4,5-trisphosphate receptors (InsP3Rs) are endoplasmic reticulum–localized channels that mediate Ca2+ release from the endoplasmic reticulum into the cytoplasm. We previously reported that an EF-hand Ca2+-binding protein, neuronal calcium sensor 1 (NCS1), binds to the InsP3R and thereby in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2019-12, Vol.294 (49), p.18923-18933
Hauptverfasser:	Nguyen, Lien D., Petri, Edward T., Huynh, Larry K., Ehrlich, Barbara E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites breast cancer Breast Neoplasms - metabolism calcium intracellular release calcium-binding protein cell line MDA-MB231 docking Female Humans Inositol 1,4,5-Trisphosphate Receptors - metabolism Neuronal Calcium-Sensor Proteins - metabolism Neuropeptides - metabolism Protein Binding protein–protein interaction Signal Transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!