The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia

Despite an increasing body of evidence demonstrating subcellular alterations in parvalbumin-positive (PV + ) interneurons in schizophrenia, their functional consequences remain elusive. Since PV + interneurons are involved in the generation of fast cortical rhythms, these changes have been hypothesi...

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Veröffentlicht in:	Scientific reports 2019-12, Vol.9 (1), p.18525-16, Article 18525
Hauptverfasser:	Metzner, Christoph, Zurowski, Bartosz, Steuber, Volker
Format:	Artikel
Sprache:	eng
Schlagworte:	631/114/116/1925 631/378/116/1925 692/53/2421 Computer applications Computer Simulation Cortex Evoked Potentials, Auditory - physiology GABAergic Neurons - metabolism Gamma Rhythm - physiology Humanities and Social Sciences Humans Interneurons Interneurons - physiology Medical innovations Mental disorders Models, Neurological multidisciplinary Oscillations Parvalbumin Parvalbumins - metabolism Schizophrenia Schizophrenia - physiopathology Science Science (multidisciplinary) Synapses Synapses - physiology Therapeutic applications
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