Trim33 (Tif1γ) is not required for skeletal muscle development or regeneration but suppresses cholecystokinin expression

The expression of Trim33 (Tif1γ) increases in skeletal muscles during regeneration and decreases upon maturation. Although Trim33 is required for the normal development of other tissues, its role in skeletal muscle is unknown. The current study aimed to define the role of Trim33 in muscle developmen...

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Veröffentlicht in:	Scientific reports 2019-12, Vol.9 (1), p.18507-6, Article 18507
Hauptverfasser:	Parks, Cassie A., Pak, Katherine, Pinal-Fernandez, Iago, Huang, Wilson, Derfoul, Assia, Mammen, Andrew L.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/89 14/63 38/77 38/91 631/337/2019 631/532/2118/2439 692/4023/1671/1668/1973 Animals Body Weight Cardiotoxins Cell Survival Cholecystokinin Cholecystokinin - metabolism Cre recombinase Exons Female Gene expression Genotype Histology Humanities and Social Sciences Male Mice Mice, Inbred C57BL Mice, Knockout multidisciplinary Muscle, Skeletal - metabolism Muscles Musculoskeletal system Regeneration RNA-Seq Satellite cells Satellite Cells, Skeletal Muscle - metabolism Science Science (multidisciplinary) siRNA Skeletal muscle Transcription Factors - metabolism Transcriptome
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