Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

Modeling studies show that increased expression of nerve growth factor is associated with increased pain. This study tested the safety and efficacy of the monoclonal antibody tanezumab — which targets nerve growth factor — for the treatment of knee pain in patients with osteoarthritis. Nerve growth...

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Veröffentlicht in:The New England journal of medicine 2010-10, Vol.363 (16), p.1521-1531
Hauptverfasser: Lane, Nancy E, Schnitzer, Thomas J, Birbara, Charles A, Mokhtarani, Masoud, Shelton, David L, Smith, Mike D, Brown, Mark T
Format: Artikel
Sprache:eng
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