PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function

Heme is an essential prosthetic group of numerous proteins and a central signaling molecule in many physiologic processes 1 , 2 . The chemical reactivity of heme requires that a network of intracellular chaperone proteins exist to avert the cytotoxic effects of free heme, but the constituents of suc...

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Veröffentlicht in:	Nature (London) 2019-11, Vol.576 (7785), p.138-142
Hauptverfasser:	Galmozzi, Andrea, Kok, Bernard P., Kim, Arthur S., Montenegro-Burke, J. Rafael, Lee, Jae Y., Spreafico, Roberto, Mosure, Sarah, Albert, Verena, Cintron-Colon, Rigo, Godio, Cristina, Webb, William R., Conti, Bruno, Solt, Laura A., Kojetin, Douglas, Parker, Christopher G., Peluso, John J., Pru, James K., Siuzdak, Gary, Cravatt, Benjamin F., Saez, Enrique
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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