Draft Genome Sequences of Mycobacterium tuberculosis Clinical Isolates from the Ural Region of Russia That Carry the pks15/1 Gene
Here, we report the draft genome sequences of 15 isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the gene, which leads to the synthesis of Pks15/1 fusion protein. Pks15/1 is involved in phenolglycolipid synthesis and biofilm formation, thus potentially contributing to...
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Veröffentlicht in: | Microbiology resource announcements 2019-12, Vol.8 (49) |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Here, we report the draft genome sequences of 15
isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the
gene, which leads to the synthesis of Pks15/1 fusion protein. Pks15/1 is involved in phenolglycolipid synthesis and biofilm formation, thus potentially contributing to the B0/W-148 lineage's enhanced virulence and drug resistance. |
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ISSN: | 2576-098X 2576-098X |
DOI: | 10.1128/MRA.01126-19 |