Draft Genome Sequences of Mycobacterium tuberculosis Clinical Isolates from the Ural Region of Russia That Carry the pks15/1 Gene

Here, we report the draft genome sequences of 15 isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the gene, which leads to the synthesis of Pks15/1 fusion protein. Pks15/1 is involved in phenolglycolipid synthesis and biofilm formation, thus potentially contributing to...

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Veröffentlicht in:Microbiology resource announcements 2019-12, Vol.8 (49)
Hauptverfasser: Shur, Kirill V, Zakharevich, Natalia V, Akimova, Natalia I, Yunes, Roman A, Frolova, Svetlana G, Maslov, Dmitry A, Danilenko, Valery N
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Sprache:eng
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Zusammenfassung:Here, we report the draft genome sequences of 15 isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the gene, which leads to the synthesis of Pks15/1 fusion protein. Pks15/1 is involved in phenolglycolipid synthesis and biofilm formation, thus potentially contributing to the B0/W-148 lineage's enhanced virulence and drug resistance.
ISSN:2576-098X
2576-098X
DOI:10.1128/MRA.01126-19