Imaging of Chemotherapy-Induced Acute Cardiotoxicity with 18F-Labeled Lipophilic Cations

Many chemotherapy agents are toxic to the heart, such that increasing numbers of cancer survivors are now living with the potentially lethal cardiovascular consequences of their treatment. Earlier and more sensitive detection of chemotherapy-induced cardiotoxicity may allow improved treatment strate...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2019-12, Vol.60 (12), p.1750-1756
Hauptverfasser:	McCluskey, Stuart P, Haslop, Anna, Coello, Christopher, Gunn, Roger N, Tate, Edward W, Southworth, Richard, Plisson, Christophe, Long, Nicholas J, Wells, Lisa A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Biomarkers Cardiology Cardiotoxicity Cations Chemotherapy Doxorubicin Fluorine isotopes Heart Imaging Lipophilic Membrane potential Mitochondria Pharmacology Positron emission Retention Single photon emission computed tomography Tomography Tracers Triazoles
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