Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients
Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional status and dietary intake with clinical variables in Mexican-mestizo SLE...
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| Veröffentlicht in: | Nutrients 2019-11, Vol.11 (11), p.2683 |
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| creator | Meza-Meza, Mónica R Vizmanos-Lamotte, Barbara Muñoz-Valle, José Francisco Parra-Rojas, Isela Garaulet, Marta Campos-López, Bertha Montoya-Buelna, Margarita Cerpa-Cruz, Sergio Martínez-López, Erika Oregon-Romero, Edith De la Cruz-Mosso, Ulises |
| description | Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional status and dietary intake with clinical variables in Mexican-mestizo SLE patients. A cross-sectional study was conducted in 130 female SLE patients, classified by the 1997 SLE American College of Rheumatology (ACR) criteria; the clinical activity was evaluated by the Mexican-Systemic Lupus Erythematosus-Disease Activity Index (Mex-SLEDAI); body mass index (BMI) by the World Health Organization (WHO) criteria; the energy calculation and nutritional intake were performed by Nutritionist Pro Diet software. SLE patients with excess weight (BMI > 25 kg/m
) showed a higher score of clinical activity (Mex-SLEDAI = 2;
= 0.003), higher clinical activity prevalence (40.9%;
= 0.039) and a significant association for high clinical activity (odds ratio (OR) = 2.52; 95% confidence interval (CI) = 1.08-5.9;
= 0.033), in comparison with patients without excess weight (BMI < 25 kg/m
). In particular, the excess weight increased the Mex-SLEDAI score (β coefficient = 1.82;
= 0.05;
= 0.005). Also, the SLE patients presented a high prevalence (%) of deficient consumption (cut-off point: |
| doi_str_mv | 10.3390/nu11112683 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6893805</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2313361206</sourcerecordid><originalsourceid>FETCH-LOGICAL-c439t-90462f01391cf8359e8d7d3f732a75cbfd74d2751f46f9a094c54d887eeae8b83</originalsourceid><addsrcrecordid>eNqFkt9rFDEQx4MottS--AdIwBcRTpNNNj9ehHK9auFA8Qc-hlx20k3dTc5NtnoP_d_N0VqrLw6EmTAfvjOTDEJPKXnFmCav40yrNUKxB-iwIbJZCMHZw3vxATrO-ZLsTRIp2GN0wKjQSlJ6iK4_wmBLSDH3YYuTx6ufDnLGXyFc9AX_CKXHyyHE4OyAT1wJV6HssI0dPg1Q7LTD57HYb4BPwQcXINaTcYj40y4XGIPD63k7Z7yadqWH0ZaU6-1DLQmx5CfokbdDhuNbf4S-nK0-L98t1u_fni9P1gvHmS4LTbhoPKFMU-cVazWoTnbMS9ZY2bqN7yTvGtlSz4XXlmjuWt4pJQEsqI1iR-jNje523ozQuVp7soPZTmGsI5hkg_k7E0NvLtKVEUozRdoq8OJWYErfZ8jFjCE7GAYbIc3ZNJwQLjVv-f9RRhkTtCGios__QS_TPMX6Enuq5Zowuade3lBuSjlP4O_6psTsd8D82YEKP7s_6R36-8fZLwamrZ8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2315490376</pqid></control><display><type>article</type><title>Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients</title><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Meza-Meza, Mónica R ; Vizmanos-Lamotte, Barbara ; Muñoz-Valle, José Francisco ; Parra-Rojas, Isela ; Garaulet, Marta ; Campos-López, Bertha ; Montoya-Buelna, Margarita ; Cerpa-Cruz, Sergio ; Martínez-López, Erika ; Oregon-Romero, Edith ; De la Cruz-Mosso, Ulises</creator><creatorcontrib>Meza-Meza, Mónica R ; Vizmanos-Lamotte, Barbara ; Muñoz-Valle, José Francisco ; Parra-Rojas, Isela ; Garaulet, Marta ; Campos-López, Bertha ; Montoya-Buelna, Margarita ; Cerpa-Cruz, Sergio ; Martínez-López, Erika ; Oregon-Romero, Edith ; De la Cruz-Mosso, Ulises</creatorcontrib><description>Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional status and dietary intake with clinical variables in Mexican-mestizo SLE patients. A cross-sectional study was conducted in 130 female SLE patients, classified by the 1997 SLE American College of Rheumatology (ACR) criteria; the clinical activity was evaluated by the Mexican-Systemic Lupus Erythematosus-Disease Activity Index (Mex-SLEDAI); body mass index (BMI) by the World Health Organization (WHO) criteria; the energy calculation and nutritional intake were performed by Nutritionist Pro Diet software. SLE patients with excess weight (BMI > 25 kg/m
) showed a higher score of clinical activity (Mex-SLEDAI = 2;
= 0.003), higher clinical activity prevalence (40.9%;
= 0.039) and a significant association for high clinical activity (odds ratio (OR) = 2.52; 95% confidence interval (CI) = 1.08-5.9;
= 0.033), in comparison with patients without excess weight (BMI < 25 kg/m
). In particular, the excess weight increased the Mex-SLEDAI score (β coefficient = 1.82;
= 0.05;
= 0.005). Also, the SLE patients presented a high prevalence (%) of deficient consumption (cut-off point: <67% of dietary adequacy) of vitamin E (100%), iodine (96%), omega 3 (93.44%), biotin (78%), vitamin K (73.33%), iron (67%), vitamin D (63.3%), potassium (59%), folic acid (56.67%), pantothenic acid (43.3%), vitamin A (41.67%) and zinc (32%). In conclusion, in SLE patients the excess weight was associated with increased clinical activity and to the presence of deficiencies in some essential nutrients ingested.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu11112683</identifier><identifier>PMID: 31698711</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adipose tissue ; Adult ; Autoimmune diseases ; Avitaminosis - complications ; Avitaminosis - epidemiology ; biotin ; Blood pressure ; Body mass index ; Body Weight - physiology ; Cholesterol ; Chronic conditions ; computer software ; confidence interval ; Confidence intervals ; Cross-Sectional Studies ; Cytokines ; Diabetes ; Diet ; Diet - statistics & numerical data ; Dietary intake ; energy ; Ethics ; Fats ; Feedback loops ; Female ; females ; folic acid ; food intake ; Helper cells ; Humans ; Hypertension ; Immune response ; Immune system ; Immunomodulation ; Inflammation ; iodine ; iron ; Lupus ; lupus erythematosus ; Lupus Erythematosus, Systemic - complications ; Lupus Erythematosus, Systemic - epidemiology ; Lupus Erythematosus, Systemic - therapy ; Lymphocytes T ; Medical prognosis ; Metabolism ; Mexico - epidemiology ; Middle Aged ; Nutrients ; nutritional status ; Nutritional Status - physiology ; Obesity ; odds ratio ; Overweight - complications ; Overweight - epidemiology ; Oxidative stress ; pantothenic acid ; patients ; potassium ; Rheumatoid arthritis ; Rheumatology ; Sodium ; Subgroups ; Systemic lupus erythematosus ; Tumor necrosis factor-TNF ; vitamin A ; Vitamin D ; vitamin E ; vitamin K ; Vitamins ; World Health Organization ; zinc</subject><ispartof>Nutrients, 2019-11, Vol.11 (11), p.2683</ispartof><rights>2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 by the authors. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-90462f01391cf8359e8d7d3f732a75cbfd74d2751f46f9a094c54d887eeae8b83</citedby><cites>FETCH-LOGICAL-c439t-90462f01391cf8359e8d7d3f732a75cbfd74d2751f46f9a094c54d887eeae8b83</cites><orcidid>0000-0003-2005-9512 ; 0000-0003-0680-0802 ; 0000-0003-4579-2294 ; 0000-0002-4066-3509 ; 0000-0002-1667-8794</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893805/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893805/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31698711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Meza-Meza, Mónica R</creatorcontrib><creatorcontrib>Vizmanos-Lamotte, Barbara</creatorcontrib><creatorcontrib>Muñoz-Valle, José Francisco</creatorcontrib><creatorcontrib>Parra-Rojas, Isela</creatorcontrib><creatorcontrib>Garaulet, Marta</creatorcontrib><creatorcontrib>Campos-López, Bertha</creatorcontrib><creatorcontrib>Montoya-Buelna, Margarita</creatorcontrib><creatorcontrib>Cerpa-Cruz, Sergio</creatorcontrib><creatorcontrib>Martínez-López, Erika</creatorcontrib><creatorcontrib>Oregon-Romero, Edith</creatorcontrib><creatorcontrib>De la Cruz-Mosso, Ulises</creatorcontrib><title>Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional status and dietary intake with clinical variables in Mexican-mestizo SLE patients. A cross-sectional study was conducted in 130 female SLE patients, classified by the 1997 SLE American College of Rheumatology (ACR) criteria; the clinical activity was evaluated by the Mexican-Systemic Lupus Erythematosus-Disease Activity Index (Mex-SLEDAI); body mass index (BMI) by the World Health Organization (WHO) criteria; the energy calculation and nutritional intake were performed by Nutritionist Pro Diet software. SLE patients with excess weight (BMI > 25 kg/m
) showed a higher score of clinical activity (Mex-SLEDAI = 2;
= 0.003), higher clinical activity prevalence (40.9%;
= 0.039) and a significant association for high clinical activity (odds ratio (OR) = 2.52; 95% confidence interval (CI) = 1.08-5.9;
= 0.033), in comparison with patients without excess weight (BMI < 25 kg/m
). In particular, the excess weight increased the Mex-SLEDAI score (β coefficient = 1.82;
= 0.05;
= 0.005). Also, the SLE patients presented a high prevalence (%) of deficient consumption (cut-off point: <67% of dietary adequacy) of vitamin E (100%), iodine (96%), omega 3 (93.44%), biotin (78%), vitamin K (73.33%), iron (67%), vitamin D (63.3%), potassium (59%), folic acid (56.67%), pantothenic acid (43.3%), vitamin A (41.67%) and zinc (32%). In conclusion, in SLE patients the excess weight was associated with increased clinical activity and to the presence of deficiencies in some essential nutrients ingested.</description><subject>Adipose tissue</subject><subject>Adult</subject><subject>Autoimmune diseases</subject><subject>Avitaminosis - complications</subject><subject>Avitaminosis - epidemiology</subject><subject>biotin</subject><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Body Weight - physiology</subject><subject>Cholesterol</subject><subject>Chronic conditions</subject><subject>computer software</subject><subject>confidence interval</subject><subject>Confidence intervals</subject><subject>Cross-Sectional Studies</subject><subject>Cytokines</subject><subject>Diabetes</subject><subject>Diet</subject><subject>Diet - statistics & numerical data</subject><subject>Dietary intake</subject><subject>energy</subject><subject>Ethics</subject><subject>Fats</subject><subject>Feedback loops</subject><subject>Female</subject><subject>females</subject><subject>folic acid</subject><subject>food intake</subject><subject>Helper cells</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Immune response</subject><subject>Immune system</subject><subject>Immunomodulation</subject><subject>Inflammation</subject><subject>iodine</subject><subject>iron</subject><subject>Lupus</subject><subject>lupus erythematosus</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Lupus Erythematosus, Systemic - epidemiology</subject><subject>Lupus Erythematosus, Systemic - therapy</subject><subject>Lymphocytes T</subject><subject>Medical prognosis</subject><subject>Metabolism</subject><subject>Mexico - epidemiology</subject><subject>Middle Aged</subject><subject>Nutrients</subject><subject>nutritional status</subject><subject>Nutritional Status - physiology</subject><subject>Obesity</subject><subject>odds ratio</subject><subject>Overweight - complications</subject><subject>Overweight - epidemiology</subject><subject>Oxidative stress</subject><subject>pantothenic acid</subject><subject>patients</subject><subject>potassium</subject><subject>Rheumatoid arthritis</subject><subject>Rheumatology</subject><subject>Sodium</subject><subject>Subgroups</subject><subject>Systemic lupus erythematosus</subject><subject>Tumor necrosis factor-TNF</subject><subject>vitamin A</subject><subject>Vitamin D</subject><subject>vitamin E</subject><subject>vitamin K</subject><subject>Vitamins</subject><subject>World Health Organization</subject><subject>zinc</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkt9rFDEQx4MottS--AdIwBcRTpNNNj9ehHK9auFA8Qc-hlx20k3dTc5NtnoP_d_N0VqrLw6EmTAfvjOTDEJPKXnFmCav40yrNUKxB-iwIbJZCMHZw3vxATrO-ZLsTRIp2GN0wKjQSlJ6iK4_wmBLSDH3YYuTx6ufDnLGXyFc9AX_CKXHyyHE4OyAT1wJV6HssI0dPg1Q7LTD57HYb4BPwQcXINaTcYj40y4XGIPD63k7Z7yadqWH0ZaU6-1DLQmx5CfokbdDhuNbf4S-nK0-L98t1u_fni9P1gvHmS4LTbhoPKFMU-cVazWoTnbMS9ZY2bqN7yTvGtlSz4XXlmjuWt4pJQEsqI1iR-jNje523ozQuVp7soPZTmGsI5hkg_k7E0NvLtKVEUozRdoq8OJWYErfZ8jFjCE7GAYbIc3ZNJwQLjVv-f9RRhkTtCGios__QS_TPMX6Enuq5Zowuade3lBuSjlP4O_6psTsd8D82YEKP7s_6R36-8fZLwamrZ8</recordid><startdate>20191106</startdate><enddate>20191106</enddate><creator>Meza-Meza, Mónica R</creator><creator>Vizmanos-Lamotte, Barbara</creator><creator>Muñoz-Valle, José Francisco</creator><creator>Parra-Rojas, Isela</creator><creator>Garaulet, Marta</creator><creator>Campos-López, Bertha</creator><creator>Montoya-Buelna, Margarita</creator><creator>Cerpa-Cruz, Sergio</creator><creator>Martínez-López, Erika</creator><creator>Oregon-Romero, Edith</creator><creator>De la Cruz-Mosso, Ulises</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2005-9512</orcidid><orcidid>https://orcid.org/0000-0003-0680-0802</orcidid><orcidid>https://orcid.org/0000-0003-4579-2294</orcidid><orcidid>https://orcid.org/0000-0002-4066-3509</orcidid><orcidid>https://orcid.org/0000-0002-1667-8794</orcidid></search><sort><creationdate>20191106</creationdate><title>Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients</title><author>Meza-Meza, Mónica R ; Vizmanos-Lamotte, Barbara ; Muñoz-Valle, José Francisco ; Parra-Rojas, Isela ; Garaulet, Marta ; Campos-López, Bertha ; Montoya-Buelna, Margarita ; Cerpa-Cruz, Sergio ; Martínez-López, Erika ; Oregon-Romero, Edith ; De la Cruz-Mosso, Ulises</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-90462f01391cf8359e8d7d3f732a75cbfd74d2751f46f9a094c54d887eeae8b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adipose tissue</topic><topic>Adult</topic><topic>Autoimmune diseases</topic><topic>Avitaminosis - complications</topic><topic>Avitaminosis - epidemiology</topic><topic>biotin</topic><topic>Blood pressure</topic><topic>Body mass index</topic><topic>Body Weight - physiology</topic><topic>Cholesterol</topic><topic>Chronic conditions</topic><topic>computer software</topic><topic>confidence interval</topic><topic>Confidence intervals</topic><topic>Cross-Sectional Studies</topic><topic>Cytokines</topic><topic>Diabetes</topic><topic>Diet</topic><topic>Diet - statistics & numerical data</topic><topic>Dietary intake</topic><topic>energy</topic><topic>Ethics</topic><topic>Fats</topic><topic>Feedback loops</topic><topic>Female</topic><topic>females</topic><topic>folic acid</topic><topic>food intake</topic><topic>Helper cells</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Immune response</topic><topic>Immune system</topic><topic>Immunomodulation</topic><topic>Inflammation</topic><topic>iodine</topic><topic>iron</topic><topic>Lupus</topic><topic>lupus erythematosus</topic><topic>Lupus Erythematosus, Systemic - complications</topic><topic>Lupus Erythematosus, Systemic - epidemiology</topic><topic>Lupus Erythematosus, Systemic - therapy</topic><topic>Lymphocytes T</topic><topic>Medical prognosis</topic><topic>Metabolism</topic><topic>Mexico - epidemiology</topic><topic>Middle Aged</topic><topic>Nutrients</topic><topic>nutritional status</topic><topic>Nutritional Status - physiology</topic><topic>Obesity</topic><topic>odds ratio</topic><topic>Overweight - complications</topic><topic>Overweight - epidemiology</topic><topic>Oxidative stress</topic><topic>pantothenic acid</topic><topic>patients</topic><topic>potassium</topic><topic>Rheumatoid arthritis</topic><topic>Rheumatology</topic><topic>Sodium</topic><topic>Subgroups</topic><topic>Systemic lupus erythematosus</topic><topic>Tumor necrosis factor-TNF</topic><topic>vitamin A</topic><topic>Vitamin D</topic><topic>vitamin E</topic><topic>vitamin K</topic><topic>Vitamins</topic><topic>World Health Organization</topic><topic>zinc</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meza-Meza, Mónica R</creatorcontrib><creatorcontrib>Vizmanos-Lamotte, Barbara</creatorcontrib><creatorcontrib>Muñoz-Valle, José Francisco</creatorcontrib><creatorcontrib>Parra-Rojas, Isela</creatorcontrib><creatorcontrib>Garaulet, Marta</creatorcontrib><creatorcontrib>Campos-López, Bertha</creatorcontrib><creatorcontrib>Montoya-Buelna, Margarita</creatorcontrib><creatorcontrib>Cerpa-Cruz, Sergio</creatorcontrib><creatorcontrib>Martínez-López, Erika</creatorcontrib><creatorcontrib>Oregon-Romero, Edith</creatorcontrib><creatorcontrib>De la Cruz-Mosso, Ulises</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Meza-Meza, Mónica R</au><au>Vizmanos-Lamotte, Barbara</au><au>Muñoz-Valle, José Francisco</au><au>Parra-Rojas, Isela</au><au>Garaulet, Marta</au><au>Campos-López, Bertha</au><au>Montoya-Buelna, Margarita</au><au>Cerpa-Cruz, Sergio</au><au>Martínez-López, Erika</au><au>Oregon-Romero, Edith</au><au>De la Cruz-Mosso, Ulises</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2019-11-06</date><risdate>2019</risdate><volume>11</volume><issue>11</issue><spage>2683</spage><pages>2683-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional status and dietary intake with clinical variables in Mexican-mestizo SLE patients. A cross-sectional study was conducted in 130 female SLE patients, classified by the 1997 SLE American College of Rheumatology (ACR) criteria; the clinical activity was evaluated by the Mexican-Systemic Lupus Erythematosus-Disease Activity Index (Mex-SLEDAI); body mass index (BMI) by the World Health Organization (WHO) criteria; the energy calculation and nutritional intake were performed by Nutritionist Pro Diet software. SLE patients with excess weight (BMI > 25 kg/m
) showed a higher score of clinical activity (Mex-SLEDAI = 2;
= 0.003), higher clinical activity prevalence (40.9%;
= 0.039) and a significant association for high clinical activity (odds ratio (OR) = 2.52; 95% confidence interval (CI) = 1.08-5.9;
= 0.033), in comparison with patients without excess weight (BMI < 25 kg/m
). In particular, the excess weight increased the Mex-SLEDAI score (β coefficient = 1.82;
= 0.05;
= 0.005). Also, the SLE patients presented a high prevalence (%) of deficient consumption (cut-off point: <67% of dietary adequacy) of vitamin E (100%), iodine (96%), omega 3 (93.44%), biotin (78%), vitamin K (73.33%), iron (67%), vitamin D (63.3%), potassium (59%), folic acid (56.67%), pantothenic acid (43.3%), vitamin A (41.67%) and zinc (32%). In conclusion, in SLE patients the excess weight was associated with increased clinical activity and to the presence of deficiencies in some essential nutrients ingested.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>31698711</pmid><doi>10.3390/nu11112683</doi><orcidid>https://orcid.org/0000-0003-2005-9512</orcidid><orcidid>https://orcid.org/0000-0003-0680-0802</orcidid><orcidid>https://orcid.org/0000-0003-4579-2294</orcidid><orcidid>https://orcid.org/0000-0002-4066-3509</orcidid><orcidid>https://orcid.org/0000-0002-1667-8794</orcidid><oa>free_for_read</oa></addata></record> |
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| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6893805 |
| source | MDPI - Multidisciplinary Digital Publishing Institute; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Adipose tissue Adult Autoimmune diseases Avitaminosis - complications Avitaminosis - epidemiology biotin Blood pressure Body mass index Body Weight - physiology Cholesterol Chronic conditions computer software confidence interval Confidence intervals Cross-Sectional Studies Cytokines Diabetes Diet Diet - statistics & numerical data Dietary intake energy Ethics Fats Feedback loops Female females folic acid food intake Helper cells Humans Hypertension Immune response Immune system Immunomodulation Inflammation iodine iron Lupus lupus erythematosus Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - epidemiology Lupus Erythematosus, Systemic - therapy Lymphocytes T Medical prognosis Metabolism Mexico - epidemiology Middle Aged Nutrients nutritional status Nutritional Status - physiology Obesity odds ratio Overweight - complications Overweight - epidemiology Oxidative stress pantothenic acid patients potassium Rheumatoid arthritis Rheumatology Sodium Subgroups Systemic lupus erythematosus Tumor necrosis factor-TNF vitamin A Vitamin D vitamin E vitamin K Vitamins World Health Organization zinc |
| title | Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T15%3A49%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relationship%20of%20Excess%20Weight%20with%20Clinical%20Activity%20and%20Dietary%20Intake%20Deficiencies%20in%20Systemic%20Lupus%20Erythematosus%20Patients&rft.jtitle=Nutrients&rft.au=Meza-Meza,%20M%C3%B3nica%20R&rft.date=2019-11-06&rft.volume=11&rft.issue=11&rft.spage=2683&rft.pages=2683-&rft.issn=2072-6643&rft.eissn=2072-6643&rft_id=info:doi/10.3390/nu11112683&rft_dat=%3Cproquest_pubme%3E2313361206%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2315490376&rft_id=info:pmid/31698711&rfr_iscdi=true |