Circular RNA ITCH suppressed prostate cancer progression by increasing HOXB13 expression via spongy miR-17-5p

Circular RNA Itchy E3 ubiquitin protein ligase (Circ-ITCH) is significantly down-regulated in various kinds of tumors, however, the mechanisms of action and functions of circITCH gene in prostate cancer (PC) are still under investigation. The mail goal of this research was to study the functional ro...

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Veröffentlicht in:	Cancer Cell International 2019-12, Vol.19 (1), p.328
Hauptverfasser:	Wang, Xuegang, Wang, Rong, Wu, Zhun, Bai, Peide
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Binding sites Cancer genetics Cancer research Cancer therapies Cell growth Cholecystokinin Chromosome 5 Circular RNA Development and progression Flow cytometry Gene expression Genes Genetic aspects Genetic research Hoxb13 gene Itch gene Ligases Luciferase Medical research Methods MicroRNA miRNA Pathogenesis Phenotypes Primary Research Prostate cancer Proteins Reporter gene RNA Studies Therapeutic applications Tissues Tumors Ubiquitin Ubiquitin-protein ligase Western blotting
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