Acupuncture inhibition of methamphetamine‐induced behaviors, dopamine release and hyperthermia in the nucleus accumbens: mediation of group II mGluR

Methamphetamine (METH) increases metabolic neuronal activity in the mesolimbic dopamine (DA) system and mediates the reinforcing effect. To explore the underlying mechanism of acupuncture intervention in reducing METH‐induced behaviors, we investigated the effect of acupuncture on locomotor activity...

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Veröffentlicht in:	Addiction biology 2019-03, Vol.24 (2), p.206-217
Hauptverfasser:	Kim, Nam Jun, Ryu, Yeonhee, Lee, Bong Hyo, Chang, Suchan, Fan, Yu, Gwak, Young S., Yang, Chae Ha, Bills, Kyle B., Steffensen, Scott C., Koo, Jin Suk, Jang, Eun Young, Kim, Hee Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Acupuncture Acupuncture Therapy Animals Body Temperature - drug effects brain temperature Central Nervous System Stimulants - pharmacology Cyclopropanes - pharmacology Dopamine Dopamine - metabolism Dopamine D1 receptors Dopamine receptors Emotional behavior Excitatory Amino Acid Antagonists - pharmacology Glutamates - pharmacology Glutamic acid receptors (metabotropic) Glycine - analogs & derivatives Glycine - pharmacology Hyperthermia Injection Locomotion - drug effects Locomotor activity Male Mesolimbic system Metabolism Methamphetamine Methamphetamine - pharmacology mGluR2/3 Nucleus accumbens Nucleus Accumbens - drug effects Rats, Sprague-Dawley Receptors, Metabotropic Glutamate - antagonists & inhibitors Receptors, Metabotropic Glutamate - physiology Rodents Temperature effects ultrasonic vocalizations Vocalization, Animal - drug effects
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