$Efficacy of the NCCV Cocktail‐1 vaccine for refractory pediatric solid tumors: A phase I clinical trial$

Efficacy of the NCCV Cocktail‐1 vaccine for refractory pediatric solid tumors: A phase I clinical trial

Pediatric refractory solid tumors are aggressive malignant diseases, resulting in an extremely poor prognosis. KOC1, FOXM1, and KIF20A are cancer antigens that could be ideal targets for anticancer immunotherapy against pediatric refractory solid tumors with positive expression for these antigens. T...

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Veröffentlicht in:	Cancer science 2019-12, Vol.110 (12), p.3650-3662
Hauptverfasser:	Akazawa, Yu, Hosono, Ako, Yoshikawa, Toshiaki, Kaneda, Hide, Nitani, Chika, Hara, Junichi, Kinoshita, Yoshiaki, Kohashi, Kenichi, Manabe, Atsushi, Fukutani, Miki, Wakabayashi, Masashi, Sato, Akihiro, Shoda, Kayoko, Shimomura, Manami, Mizuno, Shoichi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antigens Bone cancer Cancer therapies Cancer Vaccines - immunology Chemotherapy Child Clinical trials Cloning cytotoxic T lymphocyte Cytotoxicity Drug dosages Ethics Female Forkhead Box Protein M1 - immunology Glycoproteins Guardians Histocompatibility Antigens Class I - analysis Hospitals Humans Immune response Immunization Immunology Immunotherapy Interferon Kinases Kinesin - immunology Laboratories Lymphocytes T Male Medical prognosis Metastasis NCCV Cocktail‐1 Neoplasms - immunology Neoplasms - mortality Neoplasms - therapy Nervous system Original Patients pediatric refractory solid tumor Pediatrics peptide vaccine Peptides phase I Progression-Free Survival Radiation therapy Remission RNA-Binding Proteins - immunology Solid tumors Survival T-Lymphocytes, Cytotoxic - immunology Tumors Vaccination Vaccines Young Adult
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