$Ixazomib–Thalidomide–Dexamethasone for induction therapy followed by Ixazomib maintenance treatment in patients with relapsed/refractory multiple myeloma$

Ixazomib–Thalidomide–Dexamethasone for induction therapy followed by Ixazomib maintenance treatment in patients with relapsed/refractory multiple myeloma

Background Ixazomib-revlimid-dexamethason showed significant activity in relapsed/refractory multiple myeloma (RRMM). Here, we evaluate ixazomib in combination with thalidomide and dexamethasone for induction treatment followed by ixazomib maintenance therapy in RRMM patients. Methods Ninety patient...

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Veröffentlicht in:	British journal of cancer 2019-10, Vol.121 (9), p.751-757
Hauptverfasser:	Ludwig, Heinz, Poenisch, Wolfram, Knop, Stefan, Egle, Alexander, Schreder, Martin, Lechner, Daniel, Hajek, Roman, Gunsilius, Eberhard, Krenosz, Karl Jochen, Petzer, Andreas, Weisel, Katja, Niederwieser, Dietger, Einsele, Hermann, Willenbacher, Wolfgang, Melchardt, Thomas, Greil, Richard, Zojer, Niklas
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/2779/109/1941 692/4028/67/1990/804 Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biomedical and Life Sciences Biomedicine Boron Compounds - administration & dosage Boron Compounds - adverse effects Cancer Research Dexamethasone Dexamethasone - administration & dosage Dexamethasone - adverse effects Drug Resistance Epidemiology Female Glycine - administration & dosage Glycine - adverse effects Glycine - analogs & derivatives Humans Induction Chemotherapy Induction therapy Maintenance Chemotherapy Male Middle Aged Molecular Medicine Multiple myeloma Multiple Myeloma - drug therapy Oncology Patients Progression-Free Survival Regression analysis Steroids Survival Survival Rate Thalidomide Thalidomide - administration & dosage Thalidomide - adverse effects Toxicity
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