Diagnostic ability of real-time quantitative polymerase chain reaction versus immunohistochemistry for Ki-67 assessment in breast cancer: An Indian perspective

Background & objectives: Breast cancer is the most common cancer of women. Inferior prognosis in some patients has been attributed to the higher proliferative capability of the tumour. Immunohistochemistry (IHC) for Ki-67, despite being a simple and cost-effective method, has not become a valid...

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Veröffentlicht in:	Indian journal of medical research (New Delhi, India : 1994) India : 1994), 2019-09, Vol.150 (3), p.254-260
Hauptverfasser:	Mehta, Anurag, Kumar, Dushyant, Chadha, Prerna, Goswami, Malini, Vishwakarma, Gayatri, Panigrahi, Manoj, Suryavanshi, Moushumi, Panaych, Ajit
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens Biomarkers Biomarkers, Tumor - analysis Biopsy Breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - metabolism Cancer therapies Cell cycle Chemotherapy Cloning Female Gene expression Humans Immunohistochemistry Immunohistochemistry - methods India Ki-67 Antigen - analysis Medical prognosis Medical research Middle Aged Neoplasm Invasiveness Original Polymerase chain reaction Prospective Studies Protein expression Proteins Real-Time Polymerase Chain Reaction - methods Reproducibility of Results RNA, Messenger - metabolism ROC Curve Studies Tumors Variables
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