Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo applications (such as drug tracking), which make be...
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| Veröffentlicht in: | Drug delivery 2019-01, Vol.26 (1), p.1092-1103 |
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| creator | Liu, Tao Yu, Xinxin Yin, Haipeng Möschwitzer, Jan P. |
| description | Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo applications (such as drug tracking), which make best use of the advantages of drug nanocrystals. A lot of novel and advanced size reduction methods have been invented recently for special drug deliveries. In addition, some novel downstream processes have been combined with nanosuspensions, which have highly broadened its application areas (such as targeting) besides traditional routes. A large number of recent research publication regarding as nanocrystals focuses on above mentioned aspects, which have widely attracted attention. This review will focus on the recent development of nanocrystals and give an overview of regarding modification of nanocrystal by some new approaches for tailor-made drug delivery. |
| doi_str_mv | 10.1080/10717544.2019.1682721 |
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This review will focus on the recent development of nanocrystals and give an overview of regarding modification of nanocrystal by some new approaches for tailor-made drug delivery.</description><identifier>ISSN: 1071-7544</identifier><identifier>EISSN: 1521-0464</identifier><identifier>DOI: 10.1080/10717544.2019.1682721</identifier><identifier>PMID: 31735092</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Animals ; Drug Carriers - chemistry ; Drug Delivery Systems - methods ; Drug nanosuspension ; Humans ; modification of drug nanocrystals ; Nanocrystals ; Nanoparticles - chemistry ; Pharmaceutical Preparations - chemistry ; Review ; Suspensions - chemistry ; tailor-made drug delivery</subject><ispartof>Drug delivery, 2019-01, Vol.26 (1), p.1092-1103</ispartof><rights>2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2019</rights><rights>2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This work is licensed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2019 The Author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c562t-7096d1c9c4abdfc067467b4130ea8ac1f157ee5ea2c78b3a23a90f5a002ea4fc3</citedby><cites>FETCH-LOGICAL-c562t-7096d1c9c4abdfc067467b4130ea8ac1f157ee5ea2c78b3a23a90f5a002ea4fc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882472/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882472/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,27479,27901,27902,53766,53768,59116,59117</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31735092$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Tao</creatorcontrib><creatorcontrib>Yu, Xinxin</creatorcontrib><creatorcontrib>Yin, Haipeng</creatorcontrib><creatorcontrib>Möschwitzer, Jan P.</creatorcontrib><title>Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery</title><title>Drug delivery</title><addtitle>Drug Deliv</addtitle><description>Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo applications (such as drug tracking), which make best use of the advantages of drug nanocrystals. A lot of novel and advanced size reduction methods have been invented recently for special drug deliveries. In addition, some novel downstream processes have been combined with nanosuspensions, which have highly broadened its application areas (such as targeting) besides traditional routes. A large number of recent research publication regarding as nanocrystals focuses on above mentioned aspects, which have widely attracted attention. This review will focus on the recent development of nanocrystals and give an overview of regarding modification of nanocrystal by some new approaches for tailor-made drug delivery.</description><subject>Animals</subject><subject>Drug Carriers - chemistry</subject><subject>Drug Delivery Systems - methods</subject><subject>Drug nanosuspension</subject><subject>Humans</subject><subject>modification of drug nanocrystals</subject><subject>Nanocrystals</subject><subject>Nanoparticles - chemistry</subject><subject>Pharmaceutical Preparations - chemistry</subject><subject>Review</subject><subject>Suspensions - chemistry</subject><subject>tailor-made drug delivery</subject><issn>1071-7544</issn><issn>1521-0464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>0YH</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNp9kktv1DAURiMEoqXwE0CW2LDJYDt2nGwQVcWjUiU2sLZu7Oupq8Qe7GSqWfDf8TAzFWXBytb18fHjflX1mtEVox19z6hiSgqx4pT1K9Z2XHH2pDpnkrOailY8LfPC1HvorHqR8x2ltGNcPq_OGqYaSXt-Xv26tFsIBi2ZovXOG5h9DCQ6YtOyJgFCNGmXZxgzGXZkyT6UatziSBwM6cRDsMTG-5DnhDAR2GxSBHOLmbiYyAx-jKmewOJBa3H0W0y7l9UzV8z46jheVD8-f_p-9bW--fbl-urypjay5XOtaN9aZnojYLDO0FaJVg2CNRShA8MckwpRInCjuqEB3kBPnQRKOYJwprmorg9eG-FOb5KfIO10BK__FGJaa0izNyNqaobOdMhZwxpRLL0ofomDcsIahLa4Phxcm2WYsNTCnGB8JH28EvytXsetbruOC8WL4N1RkOLPBfOsJ58NjiMEjEvWvGFSNpxLUdC3_6B3cUmhfFWhJKOCqr4plDxQJsWcE7qHyzCq92HRp7DofVj0MSxl35u_X_Kw65SOAnw8AD6UNk5wH9No9Qy70k2XSmx8LvB_z_gN_P3RrA</recordid><startdate>20190101</startdate><enddate>20190101</enddate><creator>Liu, Tao</creator><creator>Yu, Xinxin</creator><creator>Yin, Haipeng</creator><creator>Möschwitzer, Jan P.</creator><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><general>Taylor & Francis Group</general><scope>0YH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88I</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M2P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20190101</creationdate><title>Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery</title><author>Liu, Tao ; 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| subjects | Animals Drug Carriers - chemistry Drug Delivery Systems - methods Drug nanosuspension Humans modification of drug nanocrystals Nanocrystals Nanoparticles - chemistry Pharmaceutical Preparations - chemistry Review Suspensions - chemistry tailor-made drug delivery |
| title | Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery |
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