Excess Glutamate May Cause Dilation of Retinal Blood Vessels in Glutamate/Aspartate Transporter-Deficient Mice

Purpose. To investigate the longitudinal findings of fundus features and spectral-domain optical coherence tomography (SD-OCT) to characterize the morphologic features in a mouse model of defective glutamate/aspartate transporter (GLAST−/− mice). Materials and Methods. The fundus findings and SD-OCT...

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Veröffentlicht in:	BioMed research international 2019, Vol.2019 (2019), p.1-11
Hauptverfasser:	Nakazawa, Mitsuru, Tanabu, Reiko, Maeda-Monai, Natsuki, Yamauchi, Kodai, Arai, Saeko, Xie, Yuting, Gonome, Takayuki, Kudo, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport System X-AG - genetics Amino Acid Transport System X-AG - metabolism Amino acids Animals Blood Blood vessels Brain research Comparative analysis Diameters Dilation Disease Models, Animal Electroretinography Evaluation Fundus Oculi Glutamate Glutamic Acid - metabolism Humans Mice Mice, Knockout Optical Coherence Tomography Oxidative stress Photography Photoreceptor Cells, Vertebrate - metabolism Photoreceptor Cells, Vertebrate - pathology Pictures Psychiatry Retina Retina - diagnostic imaging Retina - growth & development Retina - metabolism Retinal Degeneration - genetics Retinal Degeneration - metabolism Retinal Degeneration - pathology Retinal Vessels - diagnostic imaging Retinal Vessels - growth & development Retinal Vessels - metabolism Schizophrenia Science Software Statistical analysis Studies Thickness Thinning Tomography, Optical Coherence
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