Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer

Oral mucositis (OM) remains a common, debilitating toxicity of radiation therapy (RT) for head and neck cancer. The goal of this phase IIb, multi-institutional, randomized, double-blind trial was to compare the efficacy and safety of GC4419, a superoxide dismutase mimetic, with placebo to reduce the...

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Veröffentlicht in:	Journal of clinical oncology 2019-12, Vol.37 (34), p.3256-3265
Hauptverfasser:	Anderson, Carryn M, Lee, Christopher M, Saunders, Deborah P, Curtis, Amarinthia, Dunlap, Neal, Nangia, Chaitali, Lee, Arielle S, Gordon, Sharon M, Kovoor, Philip, Arevalo-Araujo, Roberto, Bar-Ad, Voichita, Peddada, Abhinand, Colvett, Kyle, Miller, Douglas, Jain, Anshu K, Wheeler, James, Blakaj, Dukagjin, Bonomi, Marcelo, Agarwala, Sanjiv S, Garg, Madhur, Worden, Francis, Holmlund, Jon, Brill, Jeffrey M, Downs, Matt, Sonis, Stephen T, Katz, Sanford, Buatti, John M
Format:	Artikel
Sprache:	eng
Schlagworte:	ORIGINAL REPORTS
Online-Zugang:	Volltext
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