Methotrexate-induced hemothorax in a woman with low-risk metastatic gestational trophoblastic disease
•Patients with invasive mole have a risk of bleeding to fragility and vascularity of the tumor.•Some patients may experience life-threatening bleeding.•Chemotherapy of patients with invasive/metastatic mole may induce bleeding.•In our patient with pulmonary metastatic mole, massive hemorrhage occurr...
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| Veröffentlicht in: | Gynecologic oncology reports 2019-11, Vol.30, p.100517, Article 100517 |
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| container_title | Gynecologic oncology reports |
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| creator | Ohki, Yuji Yamada, Hisako Taira, Yusuke Kudaka, Wataru Aoki, Yoichi |
| description | •Patients with invasive mole have a risk of bleeding to fragility and vascularity of the tumor.•Some patients may experience life-threatening bleeding.•Chemotherapy of patients with invasive/metastatic mole may induce bleeding.•In our patient with pulmonary metastatic mole, massive hemorrhage occurred 2 h after the first dose of MTX.•Our patient was successfully treated with partial resection of the bleeding tumor and additional 2 cycles of MTX. |
| doi_str_mv | 10.1016/j.gore.2019.100517 |
| format | Article |
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| ispartof | Gynecologic oncology reports, 2019-11, Vol.30, p.100517, Article 100517 |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Case Report Hemothorax Life-threatening bleeding Methotrexate Partial resection of the bleeding tumor Pulmonary metastatic mole |
| title | Methotrexate-induced hemothorax in a woman with low-risk metastatic gestational trophoblastic disease |
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