Increased mistranslation protects E. coli from protein misfolding stress due to activation of a RpoS‐dependent heat shock response

The misincorporation of an incorrect amino acid into a polypeptide during protein synthesis is considered a detrimental phenomenon. A mistranslated protein is often misfolded and degraded or nonfunctional and results in an increased cost to quality control machinery. Despite these costs, errors duri...

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Veröffentlicht in:	FEBS letters 2019-11, Vol.593 (22), p.3220-3227
Hauptverfasser:	Evans, Christopher R., Fan, Yongqiang, Ling, Jiqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	heat shock response mistranslation Research Letter Research Letters RpoH RpoS
Online-Zugang:	Volltext
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