Sequential somatic mutations upon secondary anti-HER2 treatment resistance in metastatic ERBB2S310F mutated extramammary Paget’s disease

Metastatic extramammary Paget’s disease is a rare adenocarcinoma with poor prognosis. Several reports of human epidermal growth factor receptor 2 alterations point to its pathogenic role in the disease. However, the occurrence of treatment resistance to anti-HER2 therapy demand the need for further...

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Veröffentlicht in:Oncotarget 2019-11, Vol.10 (62), p.6647-6650
Hauptverfasser: Nordmann, Thierry M., Messerli-Odermatt, Olivia, Meier, Larissa, Micaletto, Sara, Coppetti, Thomas, Nägeli, Mirjam, Kamarachev, Jivko, Kudura, Ken, Freiberger, Sandra N., Rordorf, Tamara, Mangana, Joanna, Braun, Ralph, Dummer, Reinhard
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Sprache:eng
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