A Network Pharmacology Approach to Uncover the Molecular Mechanisms of Herbal Formula Kang-Bai-Ling for Treatment of Vitiligo

Background. Kang-bai-ling (KBL), a Chinese patent medicine, has been demonstrated as an effective therapy for vitiligo in China. However, the pharmacological mechanisms of KBL have not been completely elucidated. Methods. In this study, the potential multicomponent, multitarget, and multipathway mec...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2019, Vol.2019 (2019), p.1-11
Hauptverfasser:	Zhu, Hongliu, Min, Zhongsheng, Shi, Jianxin, Xu, Manyuan, Sun, Weiguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biosynthesis Cell activation Chinese medicine Datasets Deoxyribonucleic acid Dermatology DNA Enrichment Genetics Genomes Health aspects Inflammation Lymphocytes Medicine, Botanic Medicine, Herbal Molecular modelling Neural networks NF-κB protein Oxidative stress Pathogenesis Pharmacology Physiological aspects Prolactin Protein interaction Protein-protein interactions R&D Research & development Signal transduction Skin Steroids Therapeutic applications Tumor necrosis factor Vitamin deficiency Vitiligo
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