Jieduquyuziyin Prescription-Treated Rat Serum Suppresses Activation of Peritoneal Macrophages in MRL/Lpr Lupus Mice by Inhibiting IRAK1 Signaling Pathway

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, and Jieduquyuziyin prescription (JP) is a traditional Chinese medicine (TCM) formula that has been testified to be effective for SLE treatment as an approved hospital prescription for many years in China. However, its mechanism of a...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2019, Vol.2019 (2019), p.1-13
Hauptverfasser:	Li, Rongqun, Zhuang, Aiwen, Fan, Xuemin, Deng, Xian, Hou, Xiaoli, Ji, Lina, Zhang, Xiufeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune diseases Cell activation Cell viability Chinese medicine Cytokines Disease DNA methylation Enzyme-linked immunosorbent assay Herbal medicine Herbs Immunofluorescence Immunology Inflammation Interleukin 6 IRAK protein Kinases Lipopolysaccharides Lupus Macrophages Medical treatment Medicine, Chinese MicroRNAs mRNA NF-κB protein Pathogenesis Pelodiscus sinensis Peritoneum Phosphorylation Polymerase chain reaction Proteins Signal transduction Systemic lupus erythematosus Traditional Chinese medicine TRAF6 protein Transfection Tumor necrosis factor-α
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