Quantitative Trait Locus and Integrative Genomics Revealed Candidate Modifier Genes for Ectopic Mineralization in Mouse Models of Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum, a prototype of heritable multisystem ectopic mineralization disorders, is caused by mutations in the ABCC6 gene encoding a putative efflux transporter, ABCC6. The phenotypic spectrum of pseudoxanthoma elasticum varies, and the correlation between genotype and phenotype has...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of investigative dermatology 2019-12, Vol.139 (12), p.2447-2457.e7
Hauptverfasser:	Li, Qiaoli, Philip, Vivek M., Stearns, Timothy M., Bubier, Jason A., King, Benjamin L., Low, Benjamin E., Wiles, Michael V., Saeidian, Amir Hossein, Sundberg, Beth A., Uitto, Jouni, Sundberg, John P.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!