LFA-1 antagonist (BIRT377) similarly reverses peripheral neuropathic pain in male and female mice with underlying sex divergent peripheral immune proinflammatory phenotypes

The majority of preclinical studies investigating aberrant glial-neuroimmune actions underlying neuropathic pain have focused on male rodent models. Recently, studies have shown peripheral immune cells play a more prominent role than glial cells in mediating pathological pain in females. Here, we co...

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Veröffentlicht in:Neuroimmunology and neuroinflammation 2019-01, Vol.6 (7), p.12-43
Hauptverfasser: Noor, Shahani, Sun, Melody S, Vanderwall, Arden G, Havard, Mara A, Sanchez, Jacob E, Harris, Nathan W, Nysus, Monique V, Norenberg, Jeffrey P, West, Harrison T, Wagner, Carsten R, Jantzie, Lauren L, Mellios, Nikolaos, Milligan, Erin D
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Sprache:eng
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