Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: final phase 2 results from the randomised, open-label, phase 1b–2 dose-escalation study

Summary Background Elotuzumab, an immunostimulatory monoclonal antibody targeting signalling lymphocytic activation molecule (SLAM) family member 7 (SLAMF7), selectively kills SLAMF7-expressing myeloma cells through direct activation and engagement of the innate immune system, and thus might have cl...

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Veröffentlicht in:The Lancet. Haematology 2015-12, Vol.2 (12), p.e516-e527
Hauptverfasser: Richardson, Paul G, Prof, Jagannath, Sundar, Prof, Moreau, Philippe, Prof, Jakubowiak, Andrzej J, Prof, Raab, Marc S, MD, Facon, Thierry, Prof, Vij, Ravi, Prof, White, Darrell, Prof, Reece, Donna E, MD, Benboubker, Lotfi, MD, Zonder, Jeffrey, MD, Tsao, L Claire, PhD, Anderson, Kenneth C, Prof, Bleickardt, Eric, MD, Singhal, Anil K, MD, Lonial, Sagar, Prof
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Sprache:eng
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