Reduced cerebellar gray matter is a neural signature of physical frailty

Physical frailty has been recognized as a clinical syndrome resulting from declines in various physiological systems; however, the role of the central nervous system in the pathophysiology of frailty remains unclear. The I‐Lan Longitudinal Aging Study randomly sampled community‐dwelling people aged...

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Veröffentlicht in:	Human brain mapping 2015-09, Vol.36 (9), p.3666-3676
Hauptverfasser:	Chen, Wei-Ta, Chou, Kun-Hsien, Liu, Li-Kuo, Lee, Pei-Lin, Lee, Wei-Ju, Chen, Liang-Kung, Wang, Pei-Ning, Lin, Ching-Po
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging - pathology Aging - physiology Cerebellum - pathology Cluster Analysis Female Frail Elderly Gray Matter - pathology Humans Image Processing, Computer-Assisted Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged Motor Activity muscle weakness Organ Size physical activity physical frailty Severity of Illness Index Taiwan - epidemiology voxel-based morphometry walking speed
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