A water-soluble nanoconjugate for enhanced cellular delivery of receptor-targeted MR contrast agents

ProGlo is an efficient steroid receptor-targeted magnetic resonance (MR) imaging contrast agent (CA). It has been shown to bind to the progesterone receptor (PR) and produce enhanced image contrast in PR-positive cells and tissues in vitro and in vivo. However, the hydrophobicity of the steroid targ...

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Veröffentlicht in:Bioconjugate chemistry 2019-10, Vol.30 (11), p.2947-2957
Hauptverfasser: Moore, Laura K., Caldwell, Michael A., Townsend, Taryn R., MacRenaris, Keith W., Moyle-Heyrman, Georgette, Rammohan, Nikhil, Schonher, Erika K., Burdette, Joanna E., Ho, Dean, Meade, Thomas J.
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Sprache:eng
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