Compact system for in situ laser Doppler velocimetry of blood flow

This work describes the implementation of a compact system allowing measurement of blood flow velocity using laser Doppler velocimetry in situ. The compact setup uses an optical fiber acting as an emitter and receptor of the signal. The signal is then recovered by a photodiode and processed using a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biomedical optics express 2019-11, Vol.10 (11), p.5862-5876
Hauptverfasser: Bou, Elise, Ly, Aliou, Roul, Julien, Llopis, Olivier, Vieu, Christophe, Cerf, Aline
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 5876
container_issue 11
container_start_page 5862
container_title Biomedical optics express
container_volume 10
creator Bou, Elise
Ly, Aliou
Roul, Julien
Llopis, Olivier
Vieu, Christophe
Cerf, Aline
description This work describes the implementation of a compact system allowing measurement of blood flow velocity using laser Doppler velocimetry in situ. The compact setup uses an optical fiber acting as an emitter and receptor of the signal. The signal is then recovered by a photodiode and processed using a spectrum analyzer. The prototype was successfully tested to measure microbead suspension and whole blood flow velocities in a fluidic chip. Fibers with hemispherical lenses with three different radius of curvature were investigated. This simple yet precise setup would enable the insertion of the fiber via a medical catheter to monitor blood flow velocity in non superficial vessels where previous reported techniques cannot be implemented.
doi_str_mv 10.1364/BOE.10.005862
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6865117</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2321662237</sourcerecordid><originalsourceid>FETCH-LOGICAL-c398t-8b48004fc30b0269a386bd14085697585186ab4e403960e3fbd31486d0a23aea3</originalsourceid><addsrcrecordid>eNpdkb1PwzAQxS0EohV0ZPcIQ4q_4jgLUlsKRarUBWbLSRwa5MTBTor63-MoFQJuuSf73e9OegDcYDTHlLP75W49DxqhWHByBqYExzxKkIjPf-kJmHn_gUIxliAqLsGE4iRNUUymYLmydavyDvqj73QNS-tg1UBfdT00ymsHH23bmtAP2ti8qnXnjtCWMDPWFrA09usaXJTKeD079Svw9rR-XW2i7e75ZbXYRjlNRReJjIlwQplTlCHCU0UFzwrMwoU8TWIRY8FVxjRDNOVI0zIrKGaCF0gRqrSiV-Bh5LZ9Vusi103nlJGtq2rljtKqSv79aaq9fLcHyQWPMU4C4G4E7P-NbRZbObwhQhkmhB5w8N6eljn72WvfybryuTZGNdr2XhJKMOfBO2Cj0Zo7673T5Q8bIznEJENMgx5jot8FGYHZ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2321662237</pqid></control><display><type>article</type><title>Compact system for in situ laser Doppler velocimetry of blood flow</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Bou, Elise ; Ly, Aliou ; Roul, Julien ; Llopis, Olivier ; Vieu, Christophe ; Cerf, Aline</creator><creatorcontrib>Bou, Elise ; Ly, Aliou ; Roul, Julien ; Llopis, Olivier ; Vieu, Christophe ; Cerf, Aline</creatorcontrib><description>This work describes the implementation of a compact system allowing measurement of blood flow velocity using laser Doppler velocimetry in situ. The compact setup uses an optical fiber acting as an emitter and receptor of the signal. The signal is then recovered by a photodiode and processed using a spectrum analyzer. The prototype was successfully tested to measure microbead suspension and whole blood flow velocities in a fluidic chip. Fibers with hemispherical lenses with three different radius of curvature were investigated. This simple yet precise setup would enable the insertion of the fiber via a medical catheter to monitor blood flow velocity in non superficial vessels where previous reported techniques cannot be implemented.</description><identifier>ISSN: 2156-7085</identifier><identifier>EISSN: 2156-7085</identifier><identifier>DOI: 10.1364/BOE.10.005862</identifier><identifier>PMID: 31799052</identifier><language>eng</language><publisher>Optical Society of America - OSA Publishing</publisher><subject>Biotechnology ; Engineering Sciences ; Life Sciences ; Optics ; Photonic</subject><ispartof>Biomedical optics express, 2019-11, Vol.10 (11), p.5862-5876</ispartof><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><rights>2019 Optical Society of America under the terms of the 2019 Optical Society of America</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c398t-8b48004fc30b0269a386bd14085697585186ab4e403960e3fbd31486d0a23aea3</citedby><cites>FETCH-LOGICAL-c398t-8b48004fc30b0269a386bd14085697585186ab4e403960e3fbd31486d0a23aea3</cites><orcidid>0000-0002-9593-0416 ; 0000-0003-2745-8743</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865117/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865117/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://hal.science/hal-02341223$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Bou, Elise</creatorcontrib><creatorcontrib>Ly, Aliou</creatorcontrib><creatorcontrib>Roul, Julien</creatorcontrib><creatorcontrib>Llopis, Olivier</creatorcontrib><creatorcontrib>Vieu, Christophe</creatorcontrib><creatorcontrib>Cerf, Aline</creatorcontrib><title>Compact system for in situ laser Doppler velocimetry of blood flow</title><title>Biomedical optics express</title><description>This work describes the implementation of a compact system allowing measurement of blood flow velocity using laser Doppler velocimetry in situ. The compact setup uses an optical fiber acting as an emitter and receptor of the signal. The signal is then recovered by a photodiode and processed using a spectrum analyzer. The prototype was successfully tested to measure microbead suspension and whole blood flow velocities in a fluidic chip. Fibers with hemispherical lenses with three different radius of curvature were investigated. This simple yet precise setup would enable the insertion of the fiber via a medical catheter to monitor blood flow velocity in non superficial vessels where previous reported techniques cannot be implemented.</description><subject>Biotechnology</subject><subject>Engineering Sciences</subject><subject>Life Sciences</subject><subject>Optics</subject><subject>Photonic</subject><issn>2156-7085</issn><issn>2156-7085</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpdkb1PwzAQxS0EohV0ZPcIQ4q_4jgLUlsKRarUBWbLSRwa5MTBTor63-MoFQJuuSf73e9OegDcYDTHlLP75W49DxqhWHByBqYExzxKkIjPf-kJmHn_gUIxliAqLsGE4iRNUUymYLmydavyDvqj73QNS-tg1UBfdT00ymsHH23bmtAP2ti8qnXnjtCWMDPWFrA09usaXJTKeD079Svw9rR-XW2i7e75ZbXYRjlNRReJjIlwQplTlCHCU0UFzwrMwoU8TWIRY8FVxjRDNOVI0zIrKGaCF0gRqrSiV-Bh5LZ9Vusi103nlJGtq2rljtKqSv79aaq9fLcHyQWPMU4C4G4E7P-NbRZbObwhQhkmhB5w8N6eljn72WvfybryuTZGNdr2XhJKMOfBO2Cj0Zo7673T5Q8bIznEJENMgx5jot8FGYHZ</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Bou, Elise</creator><creator>Ly, Aliou</creator><creator>Roul, Julien</creator><creator>Llopis, Olivier</creator><creator>Vieu, Christophe</creator><creator>Cerf, Aline</creator><general>Optical Society of America - OSA Publishing</general><general>Optical Society of America</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9593-0416</orcidid><orcidid>https://orcid.org/0000-0003-2745-8743</orcidid></search><sort><creationdate>20191101</creationdate><title>Compact system for in situ laser Doppler velocimetry of blood flow</title><author>Bou, Elise ; Ly, Aliou ; Roul, Julien ; Llopis, Olivier ; Vieu, Christophe ; Cerf, Aline</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c398t-8b48004fc30b0269a386bd14085697585186ab4e403960e3fbd31486d0a23aea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Biotechnology</topic><topic>Engineering Sciences</topic><topic>Life Sciences</topic><topic>Optics</topic><topic>Photonic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bou, Elise</creatorcontrib><creatorcontrib>Ly, Aliou</creatorcontrib><creatorcontrib>Roul, Julien</creatorcontrib><creatorcontrib>Llopis, Olivier</creatorcontrib><creatorcontrib>Vieu, Christophe</creatorcontrib><creatorcontrib>Cerf, Aline</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Biomedical optics express</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bou, Elise</au><au>Ly, Aliou</au><au>Roul, Julien</au><au>Llopis, Olivier</au><au>Vieu, Christophe</au><au>Cerf, Aline</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Compact system for in situ laser Doppler velocimetry of blood flow</atitle><jtitle>Biomedical optics express</jtitle><date>2019-11-01</date><risdate>2019</risdate><volume>10</volume><issue>11</issue><spage>5862</spage><epage>5876</epage><pages>5862-5876</pages><issn>2156-7085</issn><eissn>2156-7085</eissn><abstract>This work describes the implementation of a compact system allowing measurement of blood flow velocity using laser Doppler velocimetry in situ. The compact setup uses an optical fiber acting as an emitter and receptor of the signal. The signal is then recovered by a photodiode and processed using a spectrum analyzer. The prototype was successfully tested to measure microbead suspension and whole blood flow velocities in a fluidic chip. Fibers with hemispherical lenses with three different radius of curvature were investigated. This simple yet precise setup would enable the insertion of the fiber via a medical catheter to monitor blood flow velocity in non superficial vessels where previous reported techniques cannot be implemented.</abstract><pub>Optical Society of America - OSA Publishing</pub><pmid>31799052</pmid><doi>10.1364/BOE.10.005862</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-9593-0416</orcidid><orcidid>https://orcid.org/0000-0003-2745-8743</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2156-7085
ispartof Biomedical optics express, 2019-11, Vol.10 (11), p.5862-5876
issn 2156-7085
2156-7085
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6865117
source DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Biotechnology
Engineering Sciences
Life Sciences
Optics
Photonic
title Compact system for in situ laser Doppler velocimetry of blood flow
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T06%3A55%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Compact%20system%20for%20in%20situ%20laser%20Doppler%20velocimetry%20of%20blood%20flow&rft.jtitle=Biomedical%20optics%20express&rft.au=Bou,%20Elise&rft.date=2019-11-01&rft.volume=10&rft.issue=11&rft.spage=5862&rft.epage=5876&rft.pages=5862-5876&rft.issn=2156-7085&rft.eissn=2156-7085&rft_id=info:doi/10.1364/BOE.10.005862&rft_dat=%3Cproquest_pubme%3E2321662237%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2321662237&rft_id=info:pmid/31799052&rfr_iscdi=true