Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel

An increased flux of potassium ions into the mitochondrial matrix through the ATP-sensitive potassium channel (mitoK ) has been shown to provide protection against ischemia-reperfusion injury. Recently, it was proposed that the mitochondrial-targeted isoform of the renal outer medullary potassium ch...

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Veröffentlicht in:	International journal of molecular sciences 2019-10, Vol.20 (21), p.5323
Hauptverfasser:	Laskowski, Michał, Augustynek, Bartłomiej, Bednarczyk, Piotr, Żochowska, Monika, Kalisz, Justyna, O'Rourke, Brian, Szewczyk, Adam, Kulawiak, Bogusz
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - genetics Adenosine Triphosphate - metabolism Cell Line Channel gating Channels Endopeptidase K Experiments Heart Humans Hypotheses Ischemia Magnesium Magnesium - metabolism Mitochondria Mitochondrial Membranes - metabolism Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Myocardium - metabolism Permeability Pharmacology Pore formation Potassium Potassium Channels, Inwardly Rectifying - genetics Potassium Channels, Inwardly Rectifying - metabolism Potassium chloride Proteinase Proteins Reperfusion Resistance Topology
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